XUE et al. suggest adjusting for baseline serum creatinine or glomerular filtration rate in the primary analysis. The mean ± SD baseline serum creatinine concentrations for patients who had postoperative acute kidney injury (AKI) stage 0 was 0.81 (0.18); for AKI stage I it was 0.85 (0.21); and for AKI stage II/III it was 0.71 (0.18) mg/dl. When results are adjusted for baseline serum creatinine in addition to the variables in Table 1 of our report, the estimating odds ratio [95% CI] assessing the association between postoperative AKI stage 1 and long-term renal dysfunction is 2.4 [1.9, 2.9], which is virtually identical to the reported odds ratio of 2.4 [2.0, 3.0]. We therefore conclude that our published results were not biased by baseline creatinine. We further assessed the interaction between baseline creatinine and postoperative AKI...

You do not currently have access to this content.