By 2030, 1 million people in the United States will have end-stage renal disease.1 Kidney transplantation is a critically important intervention for these individuals: transplantation improves survival, quality of life, and healthcare costs compared to maintenance dialysis.2–5 Regrettably, the supply of transplantable organs remains inadequate.6 Hence, optimization of the short-term and long-term function of transplanted kidneys is critically important. Transplanted kidneys are vulnerable to acute kidney injury (AKI) related to hemodynamic instability,7 hypovolemia,8 immunologic injury, and ischemia-reperfusion injury.9 After 25 to 30% of deceased donor kidney transplantation procedures in the United States, such perioperative AKI leads to delayed graft function,10 which is typically defined as the need for dialysis within a week after transplantation.9 This incidence is likely to increase even further with increased reliance on marginal kidneys from expanded...
Normal Saline for Kidney Transplantation Surgery: Less Is More
This editorial accompanies the article on p. 621.
Accepted for publication July 22, 2021.
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Duminda N. Wijeysundera, Stuart A. McCluskey; Normal Saline for Kidney Transplantation Surgery: Less Is More. Anesthesiology 2021; 135:564–567 doi: https://doi.org/10.1097/ALN.0000000000003948
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