We read the recent article penned by Komorowski et al. with great interest, and we congratulate the authors on a well-composed and thought-provoking article addressing space exploration and the challenges of medical care, especially anesthesia, in this austere environment.

Although undersea and hyperbaric medicine is often associated with treating conditions secondary to increases in ambient pressure, such as those arising from scuba diving, it also aids in understanding and treating the pathophysiology of exposures to hypobaric conditions, like those experienced by pilots or astronauts.

In fact, entering any current space suit from a living environment, such as the International Space Station or a lunar lander, requires a decompression to a lower ambient pressure. Human trials involving decompression from sea level (1 atmosphere absolute [ATA]) to ambient pressure of the U.S. space suit (0.3 ATA) has resulted in decompression sickness in up to 20% of exposures and venous...

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