By conducting a monocentric, randomized, controlled, assessor- and patient-blinded clinical trial of 136 patients who underwent major surgery, Léger et al.1 compared the effects of opioid-free anesthesia and standard anesthesia protocols on the quality of recovery assessed by the Quality of Recovery-15 (QoR-15) score in the first 72 h after surgery. They showed that the opioid-free anesthesia protocol improved the quality of early postoperative recovery in a statistically but not clinically significant manner. As primary outcome of this study, however, the authors did not provide the preoperative QoR-15 scores and state whether they were comparable between groups in baseline characteristics of patients. Available evidence indicates that preoperative baseline QoR-15 scores are positively associated with early postoperative QoR-15 scores.2 Because the difference between preoperative and postoperative QoR-15 scores may display the features of patient’s perioperative experience changes, moreover, it has been used to compare the influence of anesthetic...
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Correspondence|
November 2024
Opioid-free Anesthesia on Quality of Recovery: Comment
Fu-Shan Xue, M.D.;
Fu-Shan Xue, M.D.
1Fujian Provincial Hospital, Fuzhou City, People’s Republic of China (F.-S.X.). xuefushan@aliyun.com or xuefushan@mail.ccmu.edu.cn
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(Accepted for publication June 28, 2024.)
Anesthesiology November 2024, Vol. 141, 1022–1023.
Citation
Fu-Shan Xue, Nong He, Cheng-Wen Li; Opioid-free Anesthesia on Quality of Recovery: Comment. Anesthesiology 2024; 141:1022–1023 doi: https://doi.org/10.1097/ALN.0000000000005137
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