Comparing the Hypotension Prediction Index to Mean Arterial Pressure and Linear Extrapolated Mean Arterial Pressure for the Prediction of Intraoperative Hypotension: A Secondary Analysis

Criticism regarding the predictive abilities of the Hypotension Prediction Index software has recently emerged¹  and it was suggested that the performance of Hypotension Prediction Index software should be compared to that of linearly extrapolated mean arterial pressure (MAP) and single MAP values.^1,2  Moreover, a strong cross-correlation was found between MAP and Hypotension Prediction Index software (–0.91 ± 0.04).³  Previously, superiority of Hypotension Prediction Index software over single MAP values was reported.⁴  Differences in data selection however, led to the publication of an erratum⁵  and it was concluded that Hypotension Prediction Index software was not superior to MAP in predicting hypotension, which was confirmed by another recent study.⁶  To further address this topic, we performed a head-to-head comparison of Hypotension Prediction Index software, MAP, and linearly extrapolated MAP as a secondary analysis from our mixed-methods study aiming to explore clinicians’ beliefs and barriers...