We thank Dr. Zhu et al. for their valuable inputs1 regarding our study.2 Dr. Zhu rightly points out that there is a relatively large proportion of zeros in our data set, which may support the use of mixed zero-inflated Poisson models. In our case, however, the use of such statistical approach was not formally indicated: the rationale underlying zero-inflation is that certain individuals might—because of some unknown factors—not be able to present values other than zero. If this is indeed the case, the logistic regression part of zero-inflated models is used to model that inability. In our trial, though, in-depth review of our longitudinal data revealed that most patients presented values other than zero on at least one of the time points. Most notably, the percentage of patients presenting zero values over the entire observation...
Anesthesia and Circulating Tumor Cells: Reply
Accepted for publication December 7, 2020.
- Views Icon Views
- Share Icon Share
- Search Site
Frédérique Hovaguimian, Julia Braun, Martin Schläpfer, Milo A. Puhan, Beatrice Beck-Schimmer; Anesthesia and Circulating Tumor Cells: Reply. Anesthesiology Newly Published on January 6, 2021. doi: https://doi.org/10.1097/ALN.0000000000003669
Download citation file: