With the Jehovah’s Witness faith encompassing more than 8 million members worldwide, there is a growing population of patients seeking surgical care without the use of blood transfusion. Additionally, there remains a select group of patients for whom compatible crossmatched blood is unavailable, due to either alloimmunization from a previous transfusion or access to an adequate blood supply. Caring for patients without transfusion requires a wide range of blood conservation strategies, taken to the extreme, in order to avoid rather than reduce transfusions.

Patient blood management programs effectively reduce blood utilization and costs while improving outcomes.2,3  Retrospective studies of patients unable to be transfused and undergoing major surgery have shown similar outcomes to matched controls when blood conservation techniques are applied.4–7  A recent meta-analysis of Jehovah’s Witness patients undergoing cardiac surgery showed...

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