ON THE COVER:
Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). In this issue of Anesthesiology, Lannemyr et al. evaluated the effects of CPB on renal oxygenation in patients undergoing cardiac surgery. They conclude that cardiopulmonary bypass impairs renal oxygenation due to renal vasoconstriction and hemodilution during and after CPB. In an accompanying Editorial View, Billings et al. explains the implications of these findings in the context of the complexities of oxygenation of the kidney.
Lannemyr et al.: Effects of Cardiopulmonary Bypass on Renal Perfusion, Filtration, and Oxygenation in Patients Undergoing Cardiac Surgery, p. 205
Billings et al.: Renal Oxygen Flux during Cardiopulmonary Bypass; Tubular Damage to Preserve Glomerular Filtration—What’s a Kidney to Do? p. 199