Of three classes of anesthetics, most EEG-based monitors fail to recognize the anesthetized state produced by ketamine. In this issue, Mashour and colleagues use high-resolution EEG and connectivity analysis to support a common EEG feature of anesthesia, including that produced by ketamine.

  • Sleigh: The Study of Consciousness Comes of Age, p. 1245

  • Lee et al.: Disruption of Frontal–Parietal Communication by Ketamine, Propofol, and Sevoflurane, p. 1264