On The Cover:

Perioperative β-adrenergic blockade appears to reduce risk of myocardial infarction, but may also increase the risk of stroke. This issue highlights retrospective data which suggest that β1-selective blockade may provide the benefits to the heart without the risk to the brain.

  • Eisenach: Patient Safety: Anesthesiology Contributions and Supplements to the American Society of Anesthesiologists’ Annual Meeting, p. 745

  • Ashes et al.: Selective β1-Antagonism with Bisoprolol Is Associated with Fewer Postoperative Strokes than Atenolol or Metoprolol: A Single-center Cohort Study of 44,092 Consecutive Patients, p. 777