I have read the very interesting and detailed article by Ramachandran et al. recently published in Anesthesiology,1  dealing with perioperative cardiopulmonary arrest and the possibility of its prediction through a retrospective database analysis. The authors showed results on the influence (predictors) of perioperative diseases, type of cardiac rhythm when pulseless activity was detected, event location (operating room, postanesthesia care unit, intensive care area, telemetry, or general ward), and other patient characteristics. Although designed to study the survival to hospital discharge as the primary outcome, and the neurological outcome (intact or affected by neurological disability) as the secondary one, I was suprised by the fact that several items usually (and in my opinion obligatory) included in anesthesia-related mortality and morbidity studies, as those cited by the authors2–4  and others,5–8  as are the surgical procedure (even grossly classified), any kind of risk stratification or score (American Society of Anesthesiologists’ physical status, etc.), and, perhaps the most important, the type of anesthetic procedure the patient was subjected to, were not included in the analysis or not showed. Otherwise, the exclusion of these informative data was not clearly explained. These are important because it could explain some of the findings of the study, as the relatively high survival rates, with good neurological outcomes of asystolic arrests, and, in part, the better outcome of cardiac arrests occurring in the operating room or in the postanesthesia care unit: for instance, asystolic cardiac arrests due to spinal anesthesia have been described as with easier resuscitation and good outcomes,2,9  and those can occur in younger patients having better physical status. Another example would be that general anesthesia is frequently chosen in the more severe patients and in high-risk surgeries, and consequently, worse prognostic should be expected if a cardiopulmonary arrest occurs.2 

The author declares no competing interests.

1.
Ramachandran
SK
,
Mhyre
J
,
Kheterpal
S
,
Christensen
RE
,
Tallman
K
,
Morris
M
,
Chan
PS
;
American Heart Association’s Get With The Guidelines-Resuscitation Investigators
:
Predictors of survival from perioperative cardiopulmonary arrests: A retrospective analysis of 2,524 events from the Get With The Guidelines-Resuscitation registry.
Anesthesiology
2013
;
119
:
1322
39
2.
Sprung
J
,
Warner
ME
,
Contreras
MG
,
Schroeder
DR
,
Beighley
CM
,
Wilson
GA
,
Warner
DO
:
Predictors of survival following cardiac arrest in patients undergoing noncardiac surgery: A study of 518,294 patients at a tertiary referral center.
Anesthesiology
2003
;
99
:
259
69
3.
Braz
LG
,
Módolo
NS
,
do Nascimento
P
Jr
,
Bruschi
BA
,
Castiglia
YM
,
Ganem
EM
,
de Carvalho
LR
,
Braz
JR
:
Perioperative cardiac arrest: A study of 53,718 anaesthetics over 9 yr from a Brazilian teaching hospital.
Br J Anaesth
2006
;
96
:
569
75
4.
Newland
MC
,
Ellis
SJ
,
Lydiatt
CA
,
Peters
KR
,
Tinker
JH
,
Romberger
DJ
,
Ullrich
FA
,
Anderson
JR
:
Anesthetic-related cardiac arrest and its mortality: A report covering 72,959 anesthetics over 10 years from a US teaching hospital.
Anesthesiology
2002
;
97
:
108
15
5.
Arbous
MS
,
Meursing
AE
,
van Kleef
JW
,
de Lange
JJ
,
Spoormans
HH
,
Touw
P
,
Werner
FM
,
Grobbee
DE
:
Impact of anesthesia management characteristics on severe morbidity and mortality.
Anesthesiology
2005
;
102
:
257
68; quiz 491–2
6.
Arbous
MS
,
Grobbee
DE
,
van Kleef
JW
,
de Lange
JJ
,
Spoormans
HH
,
Touw
P
,
Werner
FM
,
Meursing
AE
:
Mortality associated with anaesthesia: A qualitative analysis to identify risk factors.
Anaesthesia
2001
;
56
:
1141
53
7.
Hove
LD
,
Steinmetz
J
,
Christoffersen
JK
,
Møller
A
,
Nielsen
J
,
Schmidt
H
:
Analysis of deaths related to anesthesia in the period 1996–2004 from closed claims registered by the Danish Patient Insurance Association.
Anesthesiology
2007
;
106
:
675
80
8.
Cheney
FW
,
Posner
KL
,
Lee
LA
,
Caplan
RA
,
Domino
KB
:
Trends in anesthesia-related death and brain damage: A closed claims analysis.
Anesthesiology
2006
;
105
:
1081
6
9.
Kopp
SL
,
Horlocker
TT
,
Warner
ME
,
Hebl
JR
,
Vachon
CA
,
Schroeder
DR
,
Gould
AB
Jr
,
Sprung
J
:
Cardiac arrest during neuraxial anesthesia: Frequency and predisposing factors associated with survival.
Anesth Analg
2005
;
100
:
855
65