The focus of the anesthesiologist has long been largely on determining the most appropriate thresholds for transfusion in the perioperative setting. This month’s issue of Anesthesiology includes a series of articles and accompanying Editorial Views that detail risks associated with perioperative transfusion that were previously ignored, including the risk of transfusion-related acute lung injury (TRALI), transfusion-associated circulatory overload (TACO), and the risks and benefits of transfusion in surgical oncology patients.

  • Clifford et al.: Characterizing the Epidemiology of Postoperative Transfusion-related Acute Lung Injury, p. 12

  • Clifford et al.: Characterizing the Epidemiology of Perioperative Transfusion-associated Circulatory Overload, p. 21

  • Pinheiro de Almeida et al.: Transfusion Requirements in Surgical Oncology Patients: A Prospective, Randomized Controlled Trial, p. 29

  • Simmons and Pittet: Revealing the Real Risks of Perioperative Transfusion: Rise of the Machines!, p. 1

  • Cata: Perioperative Anemia and Blood Transfusions in Patients with Cancer: When the Problem, the Solution, and Their Combination Are Each Associated with Poor Outcomes, p. 3