We would like to thank Dr McGuckin for his valuable comment on our study.1  Indeed, in his mentioned review, the authors2  state: “No studies evaluated the effectiveness of antibiotic prophylaxis before PNC [perineural catheter] placement, as it is usually performed between nerve block and the start of surgery.” This gap is filled now.

We fully agree that not every patient should receive an antibiotic prophylaxis; however, practitioners might consider it in patients in whom risk factors are prominent.3,4  In subgroups at particular risk the benefit of preventing catheter-related infections with all implicated morbidity might outweigh the costs and the potential risk of promoting antimicrobial resistances generated by single-dose antibiotic prophylaxis. We also fully agree that data linkage with longer term outcome parameters is necessary.

Competing Interests

The authors declare no competing interests.

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