In this issue of Anesthesiology, two original research articles and three editorial views examine the use of data in clinical decision making.

  • Kheterpal et al.: Impact of a Novel Multiparameter Decision Support System on Intraoperative Processes of Care and Postoperative Outcomes, p. 272

  • Liu et al.: Defining the Intrinsic Cardiac Risks of Operations to Improve Preoperative Cardiac Risk Assessments, p. 283

  • Sessler: Decision Support Alerts: Importance of Validation, p. 241

  • Glance et al.: Risk Prediction Tools: The Need for Greater Transparency, p. 244

  • Javitt: Regulatory Landscape for Clinical Decision Support Technology, p. 247