STIMULATION OF CYCLIC AMP PRODUCTION BY BUPIVACAINEA POSSIBLE MECHANISM OF LOCAL ANESTHETIC CARDIOVASCULAR TOXICITY

STIMULATION OF CYCLIC AMP PRODUCTION BY BUPIVACAINE: A POSSIBLE MECHANISM OF LOCAL ANESTHETIC CARDIOVASCULAR TOXICITY

J F Butterworth, IV, MD;

J F Butterworth, IV, MD

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R C Brownlow, MD;

R C Brownlow, MD

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L R Cole, MA;

L R Cole, MA

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R C Prielipp, MD;

R C Prielipp, MD

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R Anderson, PhD

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Depts Anesthesia and Public Hlth Sciences, Wake Forest Univ Med Ctr, Winston-Salem, NC 27157–1009

STIMULATION OF CYCLIC AMP PRODUCTION BY BUPIVACAINE: A POSSIBLE MECHANISM OF LOCAL ANESTHETIC CARDIOVASCULAR TOXICITY