Barbiturate Action Is Dependent on the Conformational State of the Acetylcholine Receptor

*Instructor in Anaesthesia, Harvard Medical School; Assistant Anesthetist, Department of Anesthesia, Massachusetts General Hospital.

†Research Fellow, Department of Anesthesia, Massachusetts General Hospital, and Department of Anaesthesia, Harvard Medical School; Resident in Anesthesia, the Institut fùr Anesthesiologie, Universitat Bonn.

‡Laboratory Assistant-Specialist, Department of Anesthesia, Massachusetts General Hospital.

§Edward Mallinckrodt Professor of Pharmacology in Anesthesia, Department of Anesthesia, Massachusetts General Hospital, and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School.