In Reply:—

We appreciate the comment of Dr. Sharrock to our letter 1and review article. 2Four randomized studies are cited in which blood loss was reduced by hypotensive anesthesia. 3–6In three studies with a total of 425 patients, 3,4,6the reduction of blood loss was 13–130 ml without reduction of allogeneic blood transfusion. In one small study with 30 patients, blood loss was reduced by 500 ml, and also a reduction of allogeneic blood transfusion was observed. 5In general, the blood sparing potential of hypotensive anesthesia is limited.

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