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Table of Contents
This Month in Anesthesiology
Science, Medicine, and the Anesthesiologist
Infographics in Anesthesiology
Anesthesiology CME Program
Anesthesiology October 2015, Vol. 123, 743–744. https://doi.org/10.1097/ALN.0000000000000808
Anesthesiology October 2015, Vol. 123, 745–746. https://doi.org/10.1097/ALN.0000000000000829
Efficacy of Superimposed High-frequency Jet Ventilation Applied to Variable Degrees of Tracheal Stenosis: One Step Forward to Optimized Patient Care
Anesthesiology October 2015, Vol. 123, 747–749. https://doi.org/10.1097/ALN.0000000000000819
Journal-related Activities and Other Special Activities at the 2015 American Society of Anesthesiologists Annual Meeting
J. David Clark, M.D., Ph.D.; Brian P. Kavanagh, M.B., F.R.C.P.C.; Piyush M. Patel, M.D., F.R.C.P.C.; James P. Rathmell, M.D.; Warren S. Sandberg, M.D., Ph.D.
Anesthesiology October 2015, Vol. 123, 750–758. https://doi.org/10.1097/ALN.0000000000000843
Anesthesiology October 2015, Vol. 123, 759–762. https://doi.org/10.1097/ALN.0000000000000816
Anesthesiology October 2015, Vol. 123, 763–764. https://doi.org/10.1097/ALN.0000000000000817
Perioperative Medicine: Clinical Science
Influence of Ventilation Strategies and Anesthetic Techniques on Regional Cerebral Oximetry in the Beach Chair Position: A Prospective Interventional Study with a Randomized Comparison of Two Anesthetics
Paul Picton, M.B. Ch.B., M.R.C.P., F.R.C.A.; Andrew Dering, M.B. B.Ch., F.R.C.A.; Amir Alexander, M.P.H.; Mary Neff, M.S.N., C.R.N.A.; Bruce S. Miller, M.D., M.S.; Amy Shanks, M.S., Ph.D.; Michelle Housey, M.P.H.; George A. Mashour, M.D., Ph.D.
Anesthesiology October 2015, Vol. 123, 765–774. https://doi.org/10.1097/ALN.0000000000000798
Concurrence of Intraoperative Hypotension, Low Minimum Alveolar Concentration, and Low Bispectral Index Is Associated with Postoperative Death
Mark D. Willingham, M.D., M.C.S.I.; Elliott Karren, M.D.; Amy M. Shanks, M.S.; Michael F. O’Connor, M.D.; Eric Jacobsohn, M.B., Ch.B.; Sachin Kheterpal, M.D., M.B.A.; Michael S. Avidan, M.B., B.Ch.
Anesthesiology October 2015, Vol. 123, 775–785. https://doi.org/10.1097/ALN.0000000000000822
Perioperative Medicine: Basic Science
MicroRNA-21 Mediates Isoflurane-induced Cardioprotection against Ischemia–Reperfusion Injury via Akt/Nitric Oxide Synthase/Mitochondrial Permeability Transition Pore Pathway
Shigang Qiao, M.D.; Jessica M. Olson, Ph.D.; Mark Paterson, B.S.; Yasheng Yan, B.S.; Ivan Zaja, B.S.; Yanan Liu, Ph.D.; Matthias L. Riess, M.D., Ph.D.; Judy R. Kersten, M.D.; Mingyu Liang, Ph.D.; David C. Warltier, M.D., Ph.D.; Zeljko J. Bosnjak, Ph.D.; Zhi-Dong Ge, M.D., Ph.D.
Anesthesiology October 2015, Vol. 123, 786–798. https://doi.org/10.1097/ALN.0000000000000807
Influence of Tracheal Obstruction on the Efficacy of Superimposed High-frequency Jet Ventilation and Single-frequency Jet Ventilation
Robert Sütterlin, Ph.D.; Antonella LoMauro, M.Sc.; Stefano Gandolfi, M.Sc.; Rita Priori, Ph.D.; Andrea Aliverti, Ph.D.; Peter Frykholm, Ph.D.; Anders Larsson, Ph.D.
Anesthesiology October 2015, Vol. 123, 799–809. https://doi.org/10.1097/ALN.0000000000000818
Critical Care Medicine: Clinical Science
Low Cerebral Oxygenation Levels during Resuscitation in Out-of-hospital Cardiac Arrest Are Associated with Hyperfibrinolysis
Anne Duvekot, M.D.; Victor A. Viersen, M.D.; Simone E. Dekker, M.D.; Leo M. G. Geeraedts, Jr., M.D., Ph.D.; Lothar A. Schwarte, M.D., Ph.D.; Angelique M. E. Spoelstra-Man, M.D., Ph.D.; Peter M. van de Ven, Ph.D.; Charissa E. van den Brom, M.Sc., Ph.D.; Monique C. de Waard, M.Sc., Ph.D.; Stephan A. Loer, M.D., Ph.D.; Christa Boer, M.Sc., Ph.D.
Anesthesiology October 2015, Vol. 123, 820–829. https://doi.org/10.1097/ALN.0000000000000806
Diagnostic Accuracy of Respiratory Distress Observation Scales as Surrogates of Dyspnea Self-report in Intensive Care Unit Patients
Romain Persichini, M.D.; Frédérick Gay, M.D., Ph.D.; Matthieu Schmidt, M.D.; Julien Mayaux, M.D.; Alexandre Demoule, M.D., Ph.D.; Capucine Morélot-Panzini, M.D., Ph.D.; Thomas Similowski, M.D., Ph.D.
Anesthesiology October 2015, Vol. 123, 830–837. https://doi.org/10.1097/ALN.0000000000000805
Pain Medicine: Clinical Science
Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study
Xiaodong Liu, B.Sc., M.Eng., Ph.D.; Yuanyuan Tian, B.Med., M.Med., Ph.D.; Zhaoyu Meng, B.Sc., M.Phil., Ph.D.; Yan Chen, B.Sc., M.Sc., Ph.D.; Idy H. T. Ho, B.Sc.; Kwong Wai Choy, B.Sc., M.Sc., Ph.D.; Peter Lichtner, Ph.D.; Sunny H. Wong, M.B.Ch.B., D.Phil., M.R.C.P.; Jun Yu, M.D., Ph.D.; Tony Gin, M.D., F.R.C.A., F.A.N.Z.C.A., F.H.K.C.A.; William K. K. Wu, M.Phil., Ph.D., F.R.C.Path.; Christopher H. K. Cheng, B.Sc., Ph.D.; Matthew T. V. Chan, M.B.B.S., Ph.D., F.A.N.Z.C.A., F.H.K.C.A.
Anesthesiology October 2015, Vol. 123, 838–850. https://doi.org/10.1097/ALN.0000000000000828
Novel 10-kHz High-frequency Therapy (HF10 Therapy) Is Superior to Traditional Low-frequency Spinal Cord Stimulation for the Treatment of Chronic Back and Leg Pain: The SENZA-RCT Randomized Controlled Trial
Leonardo Kapural, M.D., Ph.D.; Cong Yu, M.D.; Matthew W. Doust, M.D.; Bradford E. Gliner, M.S.; Ricardo Vallejo, M.D., Ph.D.; B. Todd Sitzman, M.D., M.P.H.; Kasra Amirdelfan, M.D.; Donna M. Morgan, M.D.; Lora L. Brown, M.D.; Thomas L. Yearwood, M.D., Ph.D.; Richard Bundschu, M.D.; Allen W. Burton, M.D.; Thomas Yang, M.D.; Ramsin Benyamin, M.D.; Abram H. Burgher, M.D.
Anesthesiology October 2015, Vol. 123, 851–860. https://doi.org/10.1097/ALN.0000000000000774
Psychiatric Comorbidity Is Associated Prospectively with Diminished Opioid Analgesia and Increased Opioid Misuse in Patients with Chronic Low Back Pain
Ajay D. Wasan, M.D., M.Sc.; Edward Michna, M.D., J.D.; Robert R. Edwards, Ph.D., M.P.H.; Jeffrey N. Katz, M.D., M.S.; Srdjan S. Nedeljkovic, M.D.; Andrew J. Dolman, B.S.; David Janfaza, M.D.; Zach Isaac, M.D.; Robert N. Jamison, Ph.D.
Anesthesiology October 2015, Vol. 123, 861–872. https://doi.org/10.1097/ALN.0000000000000768
A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia
Kimberly Lobo, M.S., M.P.H.; Carolina Donado, M.D.; Laura Cornelissen, Ph.D.; Joseph Kim, M.A.; Rebeca Ortiz, B.A.; Roy W. A. Peake, Ph.D.; Mark Kellogg, Ph.D.; Mark E. Alexander, M.D.; David Zurakowski, Ph.D.; Katherine E. Kurgansky, M.P.H.; James Peyton, M.B.Ch.B.; Aykut Bilge, M.D., Ph.D.; Karen Boretsky, M.D.; Mary Ellen McCann, M.D., M.P.H.; Charles B. Berde, M.D., Ph.D.; Joseph Cravero, M.D.
Anesthesiology October 2015, Vol. 123, 873–885. https://doi.org/10.1097/ALN.0000000000000831
Pain Medicine: Basic Science
Neosaxitoxin in Rat Sciatic Block: Improved Therapeutic Index Using Combinations with Bupivacaine, with and without Epinephrine
Jay S. Templin, M.S.; Matthew C. Wylie, M.S., M.D.; Joseph D. Kim, M.A.; Katherine E. Kurgansky, M.P.H.; Grzegorz Gorski, M.S.; John Kheir, M.D.; David Zurakowski, Ph.D.; Gabriel Corfas, Ph.D.; Charles Berde, M.D., Ph.D.
Anesthesiology October 2015, Vol. 123, 886–898. https://doi.org/10.1097/ALN.0000000000000832
Impaired Pain-evoked Analgesia after Nerve Injury in Rats Reflects Altered Glutamate Regulation in the Locus Coeruleus
Masafumi Kimura, M.D., Ph.D.; Takashi Suto, M.D., Ph.D.; Carlos E. Morado-Urbina, B.S.; Christopher M. Peters, Ph.D.; James C. Eisenach, M.D.; Ken-Ichiro Hayashida, D.V.M., Ph.D.
Anesthesiology October 2015, Vol. 123, 899–908. https://doi.org/10.1097/ALN.0000000000000796
Neuropathic Allodynia Involves Spinal Neurexin-1β-dependent Neuroligin-1/Postsynaptic Density-95/NR2B Cascade in Rats
Tzer-Bin Lin, Ph.D.; Cheng-Yuan Lai, B.S.; Ming-Chun Hsieh, M.Sc.; Jian-Lin Jiang, M.D. Student; Jen-Kun Cheng, M.D., Ph.D.; Yat-Pang Chau, Ph.D.; Ting Ruan, Ph.D.; Gin-Den Chen, M.D.; Hsien-Yu Peng, Ph.D.
Anesthesiology October 2015, Vol. 123, 909–926. https://doi.org/10.1097/ALN.0000000000000809
Education: Images in Anesthesiology
Anesthesiology October 2015, Vol. 123, 928. https://doi.org/10.1097/ALN.0000000000000645
Education: Original Investigations in Education
Risk and Outcomes of Substance Use Disorder among Anesthesiology Residents: A Matched Cohort Analysis
David O. Warner, M.D.; Keith Berge, M.D.; Huaping Sun, Ph.D.; Ann Harman, Ph.D.; Andrew Hanson, B.S.; Darrell R. Schroeder, M.S.
Anesthesiology October 2015, Vol. 123, 929–936. https://doi.org/10.1097/ALN.0000000000000810
Education: Review Article
Education: Mind to Mind
Anesthesiology October 2015, Vol. 123, 966–967. https://doi.org/10.1097/ALN.0000000000000799
Association of Postoperative Transfusion Strategy with Short-term Outcomes in Surgical Oncology Patients
Anesthesiology October 2015, Vol. 123, 967–968. https://doi.org/10.1097/ALN.0000000000000800
Anesthesiology October 2015, Vol. 123, 968–969. https://doi.org/10.1097/ALN.0000000000000801
Transfusion Threshold Trials: The Need to Establish a Clear Difference in Transfusion Practice between Study Groups
Suzanne M. Hall, M.B.B.Ch., M.R.C.P., F.R.C.Path.; Michael J. Desborough, B.Med.Sci. (Hons.), M.B.Ch.B., M.R.C.P., F.R.C.Path.
Anesthesiology October 2015, Vol. 123, 970–971. https://doi.org/10.1097/ALN.0000000000000802
Christian von Heymann, M.D., Ph.D., D.E.A.A.; Christoph Rosenthal, M.D.; Michael Sander, M.D., Ph.D.; Felix Balzer, M.D.; Michael Kraemer, M.D.; Lutz Kaufner, M.D.
Anesthesiology October 2015, Vol. 123, 971–973. https://doi.org/10.1097/ALN.0000000000000803
Anesthesiology October 2015, Vol. 123, 974–975. https://doi.org/10.1097/ALN.0000000000000811
Anesthesiology October 2015, Vol. 123, 976–977. https://doi.org/10.1097/ALN.0000000000000826
Reviews of Educational Material
Obstetric Anesthesia Update, Volume 1: Treatment Protocols, International Anesthesiology Clinics 52(2), Spring 2014: Obstetric Anesthesia Update, Volume 2: Mechanisms and Complications, International Anesthesiology Clinics 52(3), Summer 2014
Anesthesiology October 2015, Vol. 123, 980. https://doi.org/10.1097/ALN.0000000000000773
Anesthesiology October 2015, Vol. 123, 981. https://doi.org/10.1097/ALN.0000000000000782
Anesthesiology Reflections from the Wood Library-Museum
Anesthesiology October 2015, Vol. 123, 749. https://doi.org/10.1097/01.anes.0000470957.10289.62
Anesthesiology October 2015, Vol. 123, 837. https://doi.org/10.1097/01.anes.0000470958.87417.20
Anesthesiology October 2015, Vol. 123, 860. https://doi.org/10.1097/01.anes.0000470959.95041.92
Cyclosporine-inhibitable Cerebral Drug Transport Does Not Influence Clinical Methadone Pharmacodynamics: Erratum
Anesthesiology October 2015, Vol. 123, 982. https://doi.org/10.1097/01.anes.0000470960.33159.09