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Issues

Volume 136, Issue 6
June 2022
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Anesthesiology

Table of Contents

Anesthesiology
Anesthesiology June 2022, Vol. 136, A5–A7. https://doi.org/10.1097/ALN.0000000000004266
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Editorial Board

Anesthesiology
Anesthesiology June 2022, Vol. 136, A9–A11. https://doi.org/10.1097/ALN.0000000000004245
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This Month in Anesthesiology

This Month in Anesthesiology
Anesthesiology June 2022, Vol. 136, A1–A2. https://doi.org/10.1097/ALN.0000000000004244
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Science, Medicine, and the Anesthesiologist

Science, Medicine, and the Anesthesiologist
Anesthesiology June 2022, Vol. 136, A13–A16. https://doi.org/10.1097/ALN.0000000000004246
View Articletitled, Science, Medicine, and the Anesthesiologist
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Infographics in Anesthesiology

Twitch Monitor to Choose? Quantitative Intraoperative Neuromuscular Monitoring
Holly B. Ende; James P. Rathmell; Jonathan P. Wanderer
Anesthesiology June 2022, Vol. 136, A17. https://doi.org/10.1097/ALN.0000000000004247
View Articletitled, Twitch Monitor to Choose? Quantitative Intraoperative Neuromuscular Monitoring
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Topics: intraoperative care

Anesthesiology CME Program

Instructions for Obtaining Anesthesiology Continuing Medical Education (CME) Credit
Anesthesiology June 2022, Vol. 136, A12. https://doi.org/10.1097/ALN.0000000000004242
View Articletitled, Instructions for Obtaining A<span class="small-caps">nesthesiology</span> Continuing Medical Education (CME) Credit
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Editorial

What Anesthesiology Has to Learn from Implementation Science and Quality Improvement
Meghan B. Lane-Fall, M.D., M.S.H.P., F.C.C.M.
Anesthesiology June 2022, Vol. 136, 875–876. https://doi.org/10.1097/ALN.0000000000004206
View Articletitled, What Anesthesiology Has to Learn from Implementation Science and Quality Improvement
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Topics: implementation science , quality improvement
Inflammatory Responses to Surgery and Postoperative Atrial Fibrillation
Sergey Karamnov, M.D.; Jochen D. Muehlschlegel, M.D., M.M.Sc., M.B.A.
Anesthesiology June 2022, Vol. 136, 877–879. https://doi.org/10.1097/ALN.0000000000004233
View Articletitled, Inflammatory Responses to Surgery and Postoperative Atrial Fibrillation
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Topics: atrial fibrillation , inflammatory response , surgical procedures, operative
γ-Aminobutyric Acid Type A Receptor Subtypes and Circuit Connections in Midazolam-induced Amnesia, Sedation, and Hypnosis
Stuart A. Forman, M.D., Ph.D.
Anesthesiology June 2022, Vol. 136, 880–882. https://doi.org/10.1097/ALN.0000000000004234
View Articletitled, γ-Aminobutyric Acid Type A Receptor Subtypes and Circuit Connections in Midazolam-induced Amnesia, Sedation, and Hypnosis
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Topics: amnesia , hypnosis , midazolam , sedation procedure
Optimizing Postoperative Analgesia in the Multiverse of Peripheral Nerve Catheters
Ellen M. Soffin, M.D., Ph.D.
Anesthesiology June 2022, Vol. 136, 883–884. https://doi.org/10.1097/ALN.0000000000004219
View Articletitled, Optimizing Postoperative Analgesia in the Multiverse of Peripheral Nerve Catheters
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Topics: catheters , peripheral nerves , postoperative analgesia
Anesthetic MAC: Origin, Utility, and Nomenclature Revisited
Evan D. Kharasch, M.D., Ph.D.
Anesthesiology June 2022, Vol. 136, 885–887. https://doi.org/10.1097/ALN.0000000000004217
View Articletitled, Anesthetic MAC: Origin, Utility, and Nomenclature Revisited
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Topics: minimum alveolar concentration

Special Articles

Gadgeteering for Pain Relief: The 2021 John W. Severinghaus Lecture on Translational Science
James C. Eisenach, M.D.
Anesthesiology June 2022, Vol. 136, 888–900. https://doi.org/10.1097/ALN.0000000000004207
View Articletitled, Gadgeteering for Pain Relief: The 2021 John W. Severinghaus Lecture on Translational Science
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Topics: biomedical translational science , pain , translational research

Perioperative Medicine: Clinical Science

Quantitative Neuromuscular Monitoring in Clinical Practice: A Professional Practice Change Initiative
This article has a Visual Abstract This article has an Audio Podcast
Wade A. Weigel, M.D.; Barbara L. Williams, Ph.D.; Neil A. Hanson, M.D.; C. Craig Blackmore, M.D., M.P.H.; Randy L. Johnson, Cer.A.T.; Gary M. Nissen, M.D.; Andrew B. James, M.D.; Wyndam M. Strodtbeck, M.D.
Anesthesiology June 2022, Vol. 136, 901–915. https://doi.org/10.1097/ALN.0000000000004174
View Articletitled, Quantitative Neuromuscular Monitoring in Clinical Practice: A Professional Practice Change Initiative
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Topics: anesthesia record , datasets , neuromuscular blocking agents , professional practice , surgical procedures, operative
Amiodarone with or without N-Acetylcysteine for the Prevention of Atrial Fibrillation after Thoracic Surgery: A Double-blind, Randomized Trial
This article has a Visual Abstract
David Amar, M.D.; Hao Zhang, M.D.; Mina K. Chung, M.D.; Kay See Tan, Ph.D.; Dawn Desiderio, M.D.; Bernard J. Park, M.D.; Alessia Pedoto, M.D.; Nancy Roistacher, M.D.; James M. Isbell, M.D.; Daniela Molena, M.D.; Ginger L. Milne, Ph.D.; Bryan F. Meyers, M.D.; Gregory W. Fischer, M.D.; Valerie W. Rusch, M.D.; David R. Jones, M.D.
Anesthesiology June 2022, Vol. 136, 916–926. https://doi.org/10.1097/ALN.0000000000004201
View Articletitled, Amiodarone with or without <em>N</em>-Acetylcysteine for the Prevention of Atrial Fibrillation after Thoracic Surgery: A Double-blind, Randomized Trial
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Topics: acetylcysteine , amiodarone , atrial fibrillation , prevention , thoracic surgery procedures
Intraoperative Hypotension and Acute Kidney Injury, Stroke, and Mortality during and outside Cardiopulmonary Bypass: A Retrospective Observational Cohort Study
This article has a Visual Abstract This article has an Audio Podcast
Miguel Armengol de la Hoz, M.S.; Valluvan Rangasamy, M.D., D.N.B., D.E.S.A.; Andres Brenes Bastos, M.D.; Xinling Xu, Ph.D.; Victor Novack, M.D.; Bernd Saugel, M.D.; Balachundhar Subramaniam, M.D., M.P.H., F.A.S.A.
Anesthesiology June 2022, Vol. 136, 927–939. https://doi.org/10.1097/ALN.0000000000004175
View Articletitled, Intraoperative Hypotension and Acute Kidney Injury, Stroke, and Mortality during and outside Cardiopulmonary Bypass: A Retrospective Observational Cohort Study
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Topics: inotropic agents , intraoperative hypotension , ischemic stroke , mortality , primary outcome measure
Referral Indications for Malignant Hyperthermia Susceptibility Diagnostics in Patients without Adverse Anesthetic Events in the Era of Next-generation Sequencing
This article has a Visual Abstract
Luuk R. van den Bersselaar, M.D.,M.Sc.; Anna Hellblom, M.D., M.Sc.; Mejdan Gashi, B.Sc.; Erik-Jan Kamsteeg, Ph.D.; Nicol C. Voermans, M.D., Ph.D.; Heinz Jungbluth, M.D., Ph.D.; Joris de Puydt, M.D., M.Sc.; Luc Heytens, M.D., Ph.D.; Sheila Riazi, M.D., M.Sc.; Marc M. J. Snoeck, M.D., Ph.D.
Anesthesiology June 2022, Vol. 136, 940–953. https://doi.org/10.1097/ALN.0000000000004199
View Articletitled, Referral Indications for Malignant Hyperthermia Susceptibility Diagnostics in Patients without Adverse Anesthetic Events in the Era of Next-generation Sequencing
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Topics: high-throughput nucleotide sequencing , malignant hyperthermia due to anesthesia , massively-parallel genome sequencing , patient referral , ryr1

Perioperative Medicine: Basic Science

Midazolam at Low Nanomolar Concentrations Affects Long-term Potentiation and Synaptic Transmission Predominantly via the α1–γ-Aminobutyric Acid Type A Receptor Subunit in Mice
This article has a Visual Abstract
Xènia Puig-Bosch, M.Sc.; Stefan Bieletzki, M.Sc.; Hanns Ulrich Zeilhofer, M.D.; Uwe Rudolph, M.D.; Bernd Antkowiak, Ph.D.; Gerhard Rammes, Ph.D.
Anesthesiology June 2022, Vol. 136, 954–969. https://doi.org/10.1097/ALN.0000000000004202
View Articletitled, Midazolam at Low Nanomolar Concentrations Affects Long-term Potentiation and Synaptic Transmission Predominantly via the α<sub>1</sub>–γ-Aminobutyric Acid Type A Receptor Subunit in Mice
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Topics: hippocampus , long-term potentiation , mice , midazolam , mechlorethamine

Pain Medicine: Clinical Science

Basal Infusion versus Automated Boluses and a Delayed Start Timer for “Continuous” Sciatic Nerve Blocks after Ambulatory Foot and Ankle Surgery: A Randomized Clinical Trial
CME Article This article has a Visual Abstract
John J. Finneran, IV, M.D.; Engy T. Said, M.D.; Brian P. Curran, M.D.; Matthew W. Swisher, M.D.; Jessica R. Black, M.D.; Rodney A. Gabriel, M.D., M.A.S.; Jacklynn F. Sztain, M.D.; Wendy B. Abramson, M.D.; Brenton Alexander, M.D.; Michael C. Donohue, Ph.D.; Adam Schaar, M.P.P.; Brian M. Ilfeld, M.D., M.S.
Anesthesiology June 2022, Vol. 136, 970–982. https://doi.org/10.1097/ALN.0000000000004189
View Articletitled, Basal Infusion <em>versus</em> Automated Boluses and a Delayed Start Timer for “Continuous” Sciatic Nerve Blocks after Ambulatory Foot and Ankle Surgery: A Randomized Clinical Trial
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Topics: anesthesia, local , anesthetics, local , foot , infusion procedures , operative procedure on ankle

Education: Images in Anesthesiology

Labeled Surgical Caps: A Tool to Improve Perioperative Communication
Becky J. Wong, M.D., M.S.; Aussama K. Nassar, M.D., M.Sc., F.A.C.S., F.R.C.S.C.; Sara N. Goldhaber-Fiebert, M.D.
Anesthesiology June 2022, Vol. 136, 983–984. https://doi.org/10.1097/ALN.0000000000004192
View Articletitled, Labeled Surgical Caps: A Tool to Improve Perioperative Communication
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Topics: perioperative care , surgical procedures, operative

Education: Clinical Focus Review

End-tidal Anesthetic Concentration: Monitoring, Interpretation, and Clinical Application
This article has a Video Abstract
Jan F. A. Hendrickx, M.D., Ph.D.; Andre M. De Wolf, M.D.
Anesthesiology June 2022, Vol. 136, 985–996. https://doi.org/10.1097/ALN.0000000000004218
View Articletitled, End-tidal Anesthetic Concentration: Monitoring, Interpretation, and Clinical Application
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Topics: hysteresis , impaired mobility , minimum alveolar concentration , opioids , steady state

Education: Review Article

Historical and Modern Evidence for the Role of Reward Circuitry in Emergence
Mitra Heshmati, M.D., Ph.D.; Michael R. Bruchas, Ph.D.
Anesthesiology June 2022, Vol. 136, 997–1014. https://doi.org/10.1097/ALN.0000000000004148
View Articletitled, Historical and Modern Evidence for the Role of Reward Circuitry in Emergence
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Topics: brain , brain reward pathway , dopamine , neuroscience , arousal
Advances in Neuroimaging and Monitoring to Defend Cerebral Perfusion in Noncardiac Surgery
Jonathon P. Fanning, B.Sc., M.B.B.S., Ph.D., F.R.A.C.P., F.A.N.Z.C.A., F.C.I.C.M.; Samuel F. Huth, B.Sc.; Chiara Robba, M.D., Ph.D.; Stuart M. Grieve, B.Sc., M.B.B.S., D.Phil., F.R.A.N.Z.C.R.; David Highton, M.B.Ch.B., Ph.D., F.R.C.A., F.F.I.C.M., F.A.N.Z.C.A.
Anesthesiology June 2022, Vol. 136, 1015–1038. https://doi.org/10.1097/ALN.0000000000004205
View Articletitled, Advances in Neuroimaging and Monitoring to Defend Cerebral Perfusion in Noncardiac Surgery
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Topics: brain , cerebral blood flow , cerebral perfusion , neuroimaging , perioperative care

Education: Mind to Mind

Swan Song
Lealani Mae Y. Acosta, M.D.
Anesthesiology June 2022, Vol. 136, 1039. https://doi.org/10.1097/ALN.0000000000004043
View Articletitled, Swan Song
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Topics: bedside rails , frail elderly , morphine , smiling , voice
The Burnout Dance of the Forever Pandemic
Vidya T. Raman, M.D., M.B.A.; Vanessa A. Olbrecht, M.D., M.B.A.; Allison M. Fernandez, M.D., M.B.A.
Anesthesiology June 2022, Vol. 136, 1040–1041. https://doi.org/10.1097/ALN.0000000000004169
View Articletitled, The Burnout Dance of the Forever Pandemic
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Topics: burnout , dancing , pandemics

Anesthesiology Reflections from the Wood Library-Museum

Ethereal Breath of the Gods: Always Circulating Aither
Anesthesiology June 2022, Vol. 136, 926. https://doi.org/10.1097/ALN.0000000000004237
View Articletitled, Ethereal Breath of the Gods: Always Circulating Aither
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Only Half Dead: Henry H. Hickman and “Suspended Animation”
Anesthesiology June 2022, Vol. 136, 939. https://doi.org/10.1097/ALN.0000000000004238
View Articletitled, Only Half Dead: Henry H. Hickman and “Suspended Animation”
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Correspondence

Evolution of Anesthesia Patient Safety Movement: Comment
Eli M. Brown, M.D.
Anesthesiology June 2022, Vol. 136, 1042. https://doi.org/10.1097/ALN.0000000000004185
View Articletitled, Evolution of Anesthesia Patient Safety Movement: Comment
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Evolution of Anesthesia Patient Safety Movement: Reply
Mark A. Warner, M.D.; Mary E. Warner, M.D.
Anesthesiology June 2022, Vol. 136, 1042–1043. https://doi.org/10.1097/ALN.0000000000004184
View Articletitled, Evolution of Anesthesia Patient Safety Movement: Reply
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Pressure Support Ventilation and Atelectasis: Comment
Cedrick Zaouter, M.D.; Alex Moore, M.D.; François Martin Carrier, M.D., M.Sc.; Julie Girard, M.D.; Martin Girard, M.D., M.Sc.
Anesthesiology June 2022, Vol. 136, 1043–1044. https://doi.org/10.1097/ALN.0000000000004193
View Articletitled, Pressure Support Ventilation and Atelectasis: Comment
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Pressure Support Ventilation and Atelectasis: Reply
Heejoon Jeong, M.D.; Hyun Joo Ahn, M.D., Ph.D.
Anesthesiology June 2022, Vol. 136, 1044–1045. https://doi.org/10.1097/ALN.0000000000004194
View Articletitled, Pressure Support Ventilation and Atelectasis: Reply
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Targeting Depth of Anesthesia to Prevent Delirium: Comment
Xinglong Xiong, M.D.; Dongxu Chen, Ph.D.; Xingyu Li, M.D.; Jing Shi, M.D.
Anesthesiology June 2022, Vol. 136, 1045–1046. https://doi.org/10.1097/ALN.0000000000004196
View Articletitled, Targeting Depth of Anesthesia to Prevent Delirium: Comment
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Targeting Depth of Anesthesia to Prevent Delirium: Comment
Michele Carella, M.D.; Vincent L. Bonhomme, M.D., Ph.D.
Anesthesiology June 2022, Vol. 136, 1046–1047. https://doi.org/10.1097/ALN.0000000000004208
View Articletitled, Targeting Depth of Anesthesia to Prevent Delirium: Comment
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Targeting Depth of Anesthesia to Prevent Delirium: Reply
Charles H. Brown, IV, M.D., M.H.S.; Charles W. Hogue, M.D.
Anesthesiology June 2022, Vol. 136, 1047–1048. https://doi.org/10.1097/ALN.0000000000004197
View Articletitled, Targeting Depth of Anesthesia to Prevent Delirium: Reply
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Reviews of Educational Material

Cohen’s Comprehensive Thoracic Anesthesia
Karen S. Sibert, M.D., F.A.S.A.; Steven M. Haddy, M.D., F.A.C.C.
Anesthesiology June 2022, Vol. 136, 1049–1050. https://doi.org/10.1097/ALN.0000000000004200
View Articletitled, Cohen’s Comprehensive Thoracic Anesthesia
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Topics: thoracic anesthesia

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