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Chewing gum to treat postoperative nausea and vomiting in female patients: a multicenter randomized trial

Jai N. Darvall, Ph.D., F.A.N.Z.C.A., Anurika P. De Silva, Ph.D., Britta von Ungern-Sternberg, Ph.D., F.A.N.Z.C.A., David A. Story, M.D., F.A.N.Z.C.A., Andrew J. Davidson, M.D., F.A.N.Z.C.A., Megan L. Allen, M.Clin.Epi., F.A.N.Z.C.A., An Tran-Duy, M.D., Cindy Schultz-Ferguson, M.B.A., Vi Ha, M.H.L.M., Sabine Braat, M.Sc., Kate Leslie, M.D., F.A.N.Z.C.A., on behalf of the CHEWY Trial Group and the ANZCA Clinical Trials Network

Anesthesiology. October 2024: 10.1097/ALN.0000000000005283

https://doi.org/10.1097/ALN.0000000000005283

Published: October 2024

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Articles

Application of the Estimand Framework to Anesthesia Trials

Anurika P. De Silva, Ph.D., Kate Leslie, M.D., Sabine Braat, M.Sc., Anneke C. Grobler, Ph.D.

Anesthesiology. July 2024: 141(1):13–23

https://doi.org/10.1097/ALN.0000000000004966

Published: July 2024

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Articles

Candidate Kidney Protective Strategies for Patients Undergoing Major Abdominal Surgery: A Secondary Analysis of the RELIEF Trial Cohort

David R. McIlroy, M.D., Xiaoke Feng, M.S., Matthew Shotwell, Ph.D., Sophia Wallace, M.P.H., Rinaldo Bellomo, M.D., Ph.D., Amit X. Garg, M.D., Ph.D., Kate Leslie, M.D., Philip Peyton, M.D., Ph.D., David Story, M.D., Paul S. Myles, M.P.H., D.Sc.

Anesthesiology. June 2024: 140(6):1111–1125

https://doi.org/10.1097/ALN.0000000000004957

Published: June 2024

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Articles

Postoperative Pulmonary Complications in the ENIGMA II Trial: A Post Hoc Analysis

Philip J. Peyton, M.D., Ph.D., M.B.B.S., F.A.N.Z.C.A., Grace Liskaser, M.D., Alexander Ho, M.B.B.S., Harry Marsh, M.D., F.A.N.Z.C.A., Christopher Etherington, M.B.B.S., Frederick Torlot, M.B.B.S., B.Sc., M.R.C.P., Manisha Desai, M.B.B.S., F.A.N.Z.C.A., George Perrett, M.B.B.S., B.Sc. (Hon.), F.R.C.A., Brian Chee, M.B.B.S., F.A.N.Z.C.A., Kate Leslie, M.B.B.S., M.D., M.Epid., M.Hlth.Serv.Mt., Paul S. Myles, M.D., D.Sc., M.P.H., F.A.N.Z.C.A.

Anesthesiology. April 2023: 138(4):354–363

https://doi.org/10.1097/ALN.0000000000004497

Published: April 2023

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Articles

Risk of Postoperative Pulmonary Complications: Comment

Kate Leslie, M.D., F.A.N.Z.C.A., Philip J. Peyton, M.D., F.A.N.Z.C.A., David A. Story, M.D., F.A.N.Z.C.A.

Anesthesiology. November 2021: 135(5):928–930

https://doi.org/10.1097/ALN.0000000000003978

Published: November 2021

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Articles

Sugammadex and Postoperative Pulmonary Complications: Is Stronger Evidence Required?

Kate Leslie, M.B.B.S., M.D., M.Epid., M.Hlth.Serv.Mt., Hon.D.Med.Sci., F.A.N.Z.C.A., F.A.H.M.S.

Anesthesiology. June 2020: 132(6):1299–1300

https://doi.org/10.1097/ALN.0000000000003282

Published: June 2020

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Articles

One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery

Anesthesiology. April 2020: 132(4):692–701

https://doi.org/10.1097/ALN.0000000000003158

Published: April 2020

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Articles

Genetic Analysis of Patients Who Experienced Awareness with Recall while under General Anesthesia

Jamie W. Sleigh, M.D., Kate Leslie, M.D., Andrew J. Davidson, M.D., David J. Amor, Ph.D., Peter Diakumis, M.Bioinf., Vesna Lukic, M.Sci., Paul J. Lockhart, Ph.D., Melanie Bahlo, Ph.D.

Anesthesiology. November 2019: 131(5):974–982

https://doi.org/10.1097/ALN.0000000000002877

Published: November 2019

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Articles

Pounds of Prevention but Only Ounces of Cure: The Need for More Research on the Treatment of Postoperative Nausea and Vomiting

Jai N. Darvall, M.B., B.S., M.Epid., F.A.N.Z.C.A., F.C.I.C.M., Kate Leslie, M.B., B.S., M.D., F.A.N.Z.C.A.

Anesthesiology. February 2019: 130(2):183–185

https://doi.org/10.1097/ALN.0000000000002536

Published: February 2019

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Articles

Period-dependent Associations between Hypotension during and for Four Days after Noncardiac Surgery and a Composite of Myocardial Infarction and Death: A Substudy of the POISE-2 Trial

Anesthesiology. February 2018: 128(2):317–327

https://doi.org/10.1097/ALN.0000000000001985

Published: February 2018

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Articles

Perioperative Aspirin for Prevention of Venous Thromboembolism: The PeriOperative ISchemia Evaluation-2 Trial and a Pooled Analysis of the Randomized Trials

Anesthesiology. December 2016: 125(6):1121–1129

https://doi.org/10.1097/ALN.0000000000001352

Published: December 2016

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Articles

Severe Nausea and Vomiting in the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II Trial

Paul S. Myles, M.B., B.S., M.P.H., M.D., F.C.A.I., F.A.N.Z.C.A., F.R.C.A., F.A.H.M.S., Matthew T. V. Chan, M.B., B.S., Ph.D., F.A.N.Z.C.A., F.H.K.C.A., Jessica Kasza, B.Sc., Ph.D., Michael J. Paech, M.B., B.S., D.M., F.A.N.Z.C.A., F.F.P.M.A.N.Z.C.A., F.R.A.N.Z.C.O.G., Kate Leslie, M.B., B.S., M.D., M.Epi., M.Hlth.Serv.Mt., F.A.N.Z.C.A., Philip J. Peyton, M.B., B.S., M.D., Ph.D., F.A.N.Z.C.A., Daniel I. Sessler, M.D., Guy Haller, M.D., M.Sc., Ph.D., W. Scott Beattie, M.D., Ph.D., Cameron Osborne, M.B., B.S., F.A.N.Z.C.A., J. Robert Sneyd, M.B., M.Chir., M.A., M.D., F.R.C.A., Andrew Forbes, M.Sc., Ph.D.

Anesthesiology. May 2016: 124(5):1032–1040

https://doi.org/10.1097/ALN.0000000000001057

Published: May 2016

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Articles

Nitrous Oxide and Serious Long-term Morbidity and Mortality in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II Trial

Kate Leslie, M.B.B.S., M.D., M.Epid., M.Hlth.Serv.Mt., F.A.N.Z.C.A., Paul S. Myles, M.B.B.S., M.D., M.P.H., F.A.N.Z.C.A., F.R.C.A., Jessica Kasza, B.Sc.(Hons.), Ph.D., Andrew Forbes, B.Sc.(Hons.), M.Sc., Ph.D., Philip J. Peyton, M.B.B.S., M.D., Ph.D., F.A.N.Z.C.A., Matthew T. V. Chan, M.B.B.S., F.A.N.Z.C.A., F.H.K.C.A., F.H.K.A.M., Michael J. Paech, M.B.B.S., D.M., D.R.C.O.G., F.R.C.A., F.A.N.Z.C.A., F.F.P.M.A.N.Z.C.A., F.R.A.N.Z.C.O.G. (Hon.), Daniel I. Sessler, M.D., W. Scott Beattie, M.D., Ph.D., F.R.C.P.C., P. J. Devereaux, M.D., Ph.D., F.R.C.P.C., Sophie Wallace, M.P.H.

Anesthesiology. December 2015: 123(6):1267–1280

https://doi.org/10.1097/ALN.0000000000000908

Published: December 2015

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Articles

Leukocyte DNA Damage and Wound Infection after Nitrous Oxide Administration: A Randomized Controlled Trial

Yan Chen, B.Sc., M.Sc., Ph.D., Xiaodong Liu, B.Sc., M.Eng., Ph.D., Christopher H. K. Cheng, B.Sc., Ph.D., Tony Gin, M.D., F.R.C.A., F.A.N.Z.C.A., Kate Leslie, M.B.B.S., M.D., M.Epi., F.A.N.Z.C.A., Paul Myles, M.B.B.S., M.P.H., M.D., F.C.A.R.C.S.I., F.A.N.Z.C.A., F.R.C.A., Matthew T. V. Chan, M.B.B.S., F.A.N.Z.C.A.

Anesthesiology. June 2013: 118(6):1322–1331

https://doi.org/10.1097/ALN.0b013e31829107b8

Published: June 2013

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Articles

A Cost-Benefit Analysis of the ENIGMA Trial

Alison M. Graham, M.B., B.S., Paul S. Myles, M.B., B.S., M.P.H., M.D., F.A.N.Z.C.A., Kate Leslie, M.B., B.S., M.D., M.Epi., F.A.N.Z.C.A., Matthew T.V. Chan, M.B., B.S., F.A.N.Z.C.A., Michael J. Paech, M.B., B.S., D.M., D.R.C.O.G., F.R.C.A., F.A.N.Z.C.A., F.F.P.M.A.N.Z.C.A., F.R.A.N.Z.C.O.G. (Hon), Philip Peyton, M.B., B.S., M.D., F.A.N.Z.C.A., Abdelazeem A. El Dawlatly, M.B., B.CH., M.D.

Anesthesiology. August 2011: 115(2):265–272

https://doi.org/10.1097/ALN.0b013e31821f659c

Published: August 2011

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Articles

Rapid Eye Movement Sleep and General Anesthesia

James Sleigh, M.D., Kate Leslie, M.B.B.S., M.D., M.Epi., F.A.N.Z.C.A.

Anesthesiology. April 2010: 112(4):1053

https://doi.org/10.1097/ALN.0b013e3181d423e2

Published: April 2010

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Articles

Dreaming and Electroencephalographic Changes during Anesthesia Maintained with Propofol or Desflurane

Kate Leslie, M.B., B.S., M.D., M.Epi., F.A.N.Z.C.A., Jamie Sleigh, M.B., Ch.B., M.D., Dip.App.Stat., F.A.N.Z.C.A., Michael J. Paech, M.B., B.S., D.R.C.O.G., F.R.C.A., F.A.N.Z.C.A., F.F.P.M.A.N.Z.C.A., F.R.A.N.Z.C.O.G.(Hon.), D.M., Logan Voss, B.Sc.(Hons.), Ph.D., Chiew Woon Lim, Callum Sleigh, M.Sc.

Anesthesiology. September 2009: 111(3):547–555

https://doi.org/10.1097/ALN.0b013e3181adf768

Published: September 2009

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Articles

Explanatory versus Pragmatic Trials? The Methods Make the Difference

Paul S. Myles, M.B., B.S., M.P.H., M.D., F.C.A.R.C.S.I., F.A.N.Z.C.A., F.R.C.A., Kate Leslie, M.B., B.S., M.D., M.Epi., F.A.N.Z.C.A., Matthew T. V. Chan, M.B., B.S., F.A.N.Z.C.A., Andrew Forbes, M.Sc., Ph.D., Michael J. Paech, M.B., B.S., D.M., D.R.C.O.G., F.R.C.A., F.A.N.Z.C.A., F.F.P.M.A.N.Z.C.A., F.R.A.N.Z.C.O.G.(Hon), Philip Peyton, M.B., B.S., M.D., F.A.N.Z.C.A., Brendan S. Silbert, M.B., B.S., F.A.N.Z.C.A., Elaine Pascoe, B.Sc.

Anesthesiology. March 2008: 108(3):543–544

https://doi.org/10.1097/ALN.0b013e3181654728

Published: March 2008

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Articles

Awareness in a Community-based Anesthesia Practice

Kate Leslie, M.B.B.S., M.D., M.Epi., F.A.N.Z.C.A.

Anesthesiology. October 2007: 107(4):671–672

https://doi.org/10.1097/01.anes.0000282816.86508.ae

Published: October 2007

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Articles

Avoidance of Nitrous Oxide for Patients Undergoing Major Surgery: A Randomized Controlled Trial

Paul S. Myles, M.B., B.S., M.P.H., M.D., F.C.A.R.C.S.I., F.A.N.Z.C.A., Kate Leslie, M.B., B.S., M.D., M.Epi., F.A.N.Z.C.A., Matthew T. V. Chan, M.B., B.S., F.A.N.Z.C.A., Andrew Forbes, M.Sc., Ph.D., Michael J. Paech, M.B., B.S., D.M., D.R.C.O.G., F.R.C.A., F.A.N.Z.C.A., F.F.P.M.A.N.Z.C.A., Philip Peyton, M.B., B.S., M.D., F.A.N.Z.C.A., Brendan S. Silbert, M.B., B.S., F.A.N.Z.C.A., Elaine Pascoe, B.Sc., the ENIGMA Trial Group

Anesthesiology. August 2007: 107(2):221–231

https://doi.org/10.1097/01.anes.0000270723.30772.da

Published: August 2007

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NARROW

Chewing gum to treat postoperative nausea and vomiting in female patients: a multicenter randomized trial

Application of the Estimand Framework to Anesthesia Trials

Candidate Kidney Protective Strategies for Patients Undergoing Major Abdominal Surgery: A Secondary Analysis of the RELIEF Trial Cohort

Postoperative Pulmonary Complications in the ENIGMA II Trial: A Post Hoc Analysis

Risk of Postoperative Pulmonary Complications: Comment

Sugammadex and Postoperative Pulmonary Complications: Is Stronger Evidence Required?

One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery

Genetic Analysis of Patients Who Experienced Awareness with Recall while under General Anesthesia

Pounds of Prevention but Only Ounces of Cure: The Need for More Research on the Treatment of Postoperative Nausea and Vomiting

Period-dependent Associations between Hypotension during and for Four Days after Noncardiac Surgery and a Composite of Myocardial Infarction and Death: A Substudy of the POISE-2 Trial

Perioperative Aspirin for Prevention of Venous Thromboembolism: The PeriOperative ISchemia Evaluation-2 Trial and a Pooled Analysis of the Randomized Trials

Severe Nausea and Vomiting in the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II Trial

Nitrous Oxide and Serious Long-term Morbidity and Mortality in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II Trial

Leukocyte DNA Damage and Wound Infection after Nitrous Oxide Administration: A Randomized Controlled Trial

A Cost-Benefit Analysis of the ENIGMA Trial

Rapid Eye Movement Sleep and General Anesthesia

Dreaming and Electroencephalographic Changes during Anesthesia Maintained with Propofol or Desflurane

Explanatory versus Pragmatic Trials? The Methods Make the Difference

Awareness in a Community-based Anesthesia Practice

Avoidance of Nitrous Oxide for Patients Undergoing Major Surgery: A Randomized Controlled Trial

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