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Laurence E. Mather
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Articles

When Regional Anesthesia Met Pharmacokinetics

Laurence E. Mather, D.Med.Sc., Ph.D., M.Sc., Dip.Appl.Chem., F.A.N.Z.C.A. (Hon.), F.R.C.A. (Hon.), F.F.P.M.A.N.Z.C.A. (Hon.), Geoffrey T. Tucker, B.Pharm., Ph.D., D.Sc. (Hon.), F.R.C.P. (Hon.), F.R.C.A., F.F.P.M. (Hon.), F.B.Pharmacol.S. (Hon.), F.B.Toxicol.S., F.C.C.P., F.F.I.P., M.A.S.C.E.P.T. (Hon.), M.I.S.S.X. (Hon.)
Publication: Anesthesiology
Anesthesiology. April 2022: 136(4):588–593
https://doi.org/10.1097/ALN.0000000000004143
Published: April 2022
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Direct Cardiac Effects of Coronary Site-directed Thiopental and Its Enantiomers: A Comparison to Propofol in Conscious Sheep

Laurence E. Mather, Ph.D., Colin C. Duke, Ph.D., Leigh A. Ladd, B.V.Sc., Susan E. Copeland, M.Vet.Clin.Stud., Gabrielle Gallagher, B.Med.Sci.(Hons), Dennis H.T. Chang, Ph.D.
Publication: Anesthesiology
Anesthesiology. August 2004: 101(2):354–364
https://doi.org/10.1097/00000542-200408000-00016
Published: August 2004
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Effects of Imposed Acid–Base Derangement on the Cardiovascular Effects and Pharmacokinetics of Bupivacaine and Thiopental

Laurence E. Mather, Ph.D., Leigh A. Ladd, B.V.Sc., Susan E. Copeland, M.Vet.Clin.Stud., Dennis H.-T. Chang, Ph.D.
Publication: Anesthesiology
Anesthesiology. June 2004: 100(6):1457–1468
https://doi.org/10.1097/00000542-200406000-00018
Published: June 2004
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Neurally-mediated Cardiotoxicity of Local Anesthetics: Direct Effect of Seizures or of Local Anesthetics?: In Reply:—

Leigh A. Ladd, B.VSc., Susan E. Copeland, M.VetClinStud, Laurence E. Mather, Ph.D.*
Publication: Anesthesiology
Anesthesiology. May 2003: 98(5):1296–1297
https://doi.org/10.1097/00000542-200305000-00045
Published: May 2003
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Effects of CNS Site-directed Carotid Arterial Infusions of Bupivacaine, Levobupivacaine, and Ropivacaine in Sheep

Leigh A. Ladd, B.VSc., Dennis H-T. Chang, Ph.D., Kylie A. Wilson, B.Sc., Susan E. Copeland, M.VetClinStud., John L. Plummer, Ph.D., Laurence E. Mather, Ph.D.
Publication: Anesthesiology
Anesthesiology. August 2002: 97(2):418–428
https://doi.org/10.1097/00000542-200208000-00020
Published: August 2002
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Calculation of the Permeability Coefficient Should Take into Account the Fact That Most Drugs Are Weak Electrolytes

René J. Grouls, Ph.D., Erik H. Korsten, M.D., Ph.D., Ludo J. Hellebrekers, D.V.M., Ph.D., Eric W. Ackerman, Pharm.D., Laurence E. Mather, Ph.D.
Publication: Anesthesiology
Anesthesiology. November 2001: 95(5):1300–1301
https://doi.org/10.1097/00000542-200111000-00045
Published: November 2001
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Lack of Whole-body Pharmacokinetic Differences of Halothane Enantiomers in the Rat

Laurence E. Mather, Ph.D., F.A.N.Z.C.A., Bronwyn L. Fryirs, B.App.Sci.(Hons), Colin C. Duke, Ph.D., Michael J. Cousins, M.D., F.A.N.Z.C.A.
Publication: Anesthesiology
Anesthesiology. January 2000: 92(1):190
https://doi.org/10.1097/00000542-200001000-00031
Published: January 2000
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Pharmacokinetics of Thiopental Enantiomers during and following Prolonged High-dose Therapy

Dennis J. Cordato, F.R.A.C.P., Laurence E. Mather, Ph.D., Annette S. Gross, Ph.D., Geoffrey K. Herkes, Ph.D.
Publication: Anesthesiology
Anesthesiology. December 1999: 91(6):1693
https://doi.org/10.1097/00000542-199912000-00022
Published: December 1999
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Should Epinephrine Be Used to Treat Local Anesthetic-induced Cardiotoxicity?

James E. Heavner, D.V.M., Ph.D., Laurence E. Mather, Ph.D., Mikko Pitkänen, M.D., Ph.D., Bing Shi, M.D.
Publication: Anesthesiology
Anesthesiology. May 1994: 80(5):1179
https://doi.org/10.1097/00000542-199405000-00031
Published: May 1994
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Intrathecal and Epidural Administration of Opioids

Lawrence J. Saldman, M.D., Michael J. Cousins, M.D., F.F.A.R.A.C.S., Laurence E. Mather, M.Sc., Ph.D.
Publication: Anesthesiology
Anesthesiology. September 1984: 61(3):276–310
https://doi.org/10.1097/00000542-198409000-00008
Published: September 1984
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Arterial and Venous Plasma Levels of Bupivacaine Following Epidural and Intercostal Nerve Blocks

Daniel C. Moore, M.D., Laurence E. Mather, Ph.D., Phillip O. Bridenbaugh, M.D., L. Donald Bridenbaugh, M.D., Robert I. Balfour, M.D., Donald F. Lysons, M.D., William G. Horton, M.D.
Publication: Anesthesiology
Anesthesiology. July 1976: 45(1):39–45
https://doi.org/10.1097/00000542-197607000-00008
Published: July 1976
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Articles

Drug Interactions

Laurence E. Mather, Ph.D.
Publication: Anesthesiology
Anesthesiology. July 1975: 43(1):136
https://doi.org/10.1097/00000542-197507000-00042
Published: July 1975
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Effects of Peridural Block: V. Properties Circulatory Effects, and Blood Levels of Etidocaine and Lidocaine

Michael Stanton-Hicks, M.B., B.S., F.F.A.R.C.S., Terence M. Murphy, M.B.; Ch.B., F.F.A.R.C.S., John J. Bonica, M.D., F.F.A.R.C.S., Peter U. Berges, M.D., Laurence E. Mather, Ph.D., Geoffrey T. Tucker, Ph.D.
Publication: Anesthesiology
Anesthesiology. April 1975: 42(4):398–406
https://doi.org/10.1097/00000542-197504000-00006
Published: April 1975
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