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Articles

Morphine Exacerbates Postfracture Nociceptive Sensitization, Functional Impairment, and Microglial Activation in Mice

Wen-Wu Li, Ph.D., Karen-Amanda Irvine, Ph.D., Peyman Sahbaie, M.D., Tian-Zhi Guo, M.D., Xiao-you Shi, M.D., Vivianne L. Tawfik, M.D., Ph.D., Wade S. Kingery, M.D., J. David Clark, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. February 2019: 130(2):292–308
https://doi.org/10.1097/ALN.0000000000002495
Published: February 2019
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Exercise Reverses Nociceptive Sensitization, Upregulated Neuropeptide Signaling, Inflammatory Changes, Anxiety, and Memory Impairment in a Mouse Tibia Fracture Model

Xiaoyou Shi, M.D., Tian-zhi Guo, M.D., Wenwu Li, Ph.D., Peyman Sahbaie, M.D., Kenner C. Rice, Ph.D., Agnieszka Sulima, Ph.D., J. David Clark, M.D., Ph.D., Wade S. Kingery, M.D.
Publication: Anesthesiology
Anesthesiology. September 2018: 129(3):557–575
https://doi.org/10.1097/ALN.0000000000002332
Published: September 2018
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Substance P Signaling Controls Mast Cell Activation, Degranulation, and Nociceptive Sensitization in a Rat Fracture Model of Complex Regional Pain Syndrome

Wen-Wu Li, Ph.D., Tian-Zhi Guo, M.D., De-yong Liang, Ph.D., Yuan Sun, Ph.D., Wade S. Kingery, M.D., J. David Clark, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. April 2012: 116(4):882–895
https://doi.org/10.1097/ALN.0b013e31824bb303
Published: April 2012
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Articles

Sedative but Not Analgesic α 2 Agonist Tolerance Is Blocked by NMDA Receptor and Nitric Oxide Synthase Inhibitors

M. Frances Davies, Ph.D., Kristina Reid, B.S., Tian-Zhi Guo, M.D., Geeta S. Agashe, M.D., Yogen K. Amin, M.B. Ch.B., F.R.C.A., Mervyn Maze, M.B. Ch.B., F.R.C.A., F.R.C.P.
Publication: Anesthesiology
Anesthesiology. July 2001: 95(1):184–191
https://doi.org/10.1097/00000542-200107000-00029
Published: July 2001
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Articles

The Analgesic Action of Nitrous Oxide Is Dependent on the Release of Norepinephrine in the Dorsal Horn of the Spinal Cord

Chousheng Zhang, M.D., Frances M. Davies, Ph.D., Tian-Zhi Guo, M.D., Mervyn Maze, M.B., Ch.B., F.R.C.P.
Publication: Anesthesiology
Anesthesiology. November 1999: 91(5):1401
https://doi.org/10.1097/00000542-199911000-00033
Published: November 1999
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Articles

Nitrous Oxide Produces Antinociceptive Response via α 2B and/or α 2C Adrenoceptor Subtypes in Mice

Tian-Zhi Guo, MD, Frances M. Davies, PhD, Wade S. Kingery, MD, Andrew J. Patterson, MD, Lee E. Limbird, PhD, Mervyn Maze, MB, ChB, FRCP
Publication: Anesthesiology
Anesthesiology. February 1999: 90(2):470–476
https://doi.org/10.1097/00000542-199902000-00022
Published: February 1999
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Articles

Chronic Desipramine Treatment Desensitizes the Rat to Anesthetic and Antinociceptive Effects of the α 2-adrenergic Agonist Dexmedetomidine

Tian-Zhi Guo, MD, Kristina Reid, BS, Frances M. Davies, PhD, Carla Nacif-Coelho, MD, Bradford C. Rabin, BS, Fernando Gonzalez, Mervyn Maze, MB, FRCP
Publication: Anesthesiology
Anesthesiology. June 1998: 88(6):1634–1642
https://doi.org/10.1097/00000542-199806000-00028
Published: June 1998
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Articles

Antinociceptive Response to Nitrous Oxide Is Mediated by Supraspinal Opiate and Spinal α 2 Adrenergic Receptors in the Rat

Tian-Zhi Guo, MD, Lawrence Poree, PhD, Wendy Golden, BA, Joshua Stein, BA, Masahiko Fujinaga, MD, Mervyn Maze, MB, ChB
Publication: Anesthesiology
Anesthesiology. October 1996: 85(4):846–852
https://doi.org/10.1097/00000542-199610000-00020
Published: October 1996
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Sympatholytic and Minimum Anesthetic Concentration-sparing Responses are Preserved in Rats Rendered Tolerant to the Hypnotic and Analgesic Action of Dexmedetomidine, a Selective α 2 -adrenergic Agonist

Bradford C. Rabin, BA, Kristina Reid, BS, Tian-Zhi Guo, MD, Eva Gustafsson, MD, Chousheng Zhang, MD, Mervyn Maze, MBChB
Publication: Anesthesiology
Anesthesiology. September 1996: 85(3):565–573.
https://doi.org/10.1097/00000542-199609000-00016
Published: September 1996
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Dexmedetomidine Injection into the Locus Ceruleus Produces Antinociception

Tian-Zhi Guo, MD, Jian-Yu Jiang, MD, Ann E. Buttermann, MD, PhD, Mervyn Maze, MB, ChB
Publication: Anesthesiology
Anesthesiology. April 1996: 84(4):873–881.
https://doi.org/10.1097/00000542-199604000-00015
Published: April 1996
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Articles

Role of Pertussis Toxin-sensitive G-Proteins in the Analgesic and Anesthetic Actions of α 2 -Adrenergic Agonists in the Rat

Yukio Hayashi, MD, Bradford C. Rabin, BS, Tian-Zhi Guo, MD, Mervyn Maze, MB, ChB
Publication: Anesthesiology
Anesthesiology. October 1995: 83(4):816–822.
https://doi.org/10.1097/00000542-199510000-00022
Published: October 1995
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Articles

Desensitization to the Behavioral Effects of α 2 -Adrenergic Agonists in Rats

Yukio Hayashi, MD, Tian-Zhi Guo, MD, Mervyn Maze, MB, ChB
Publication: Anesthesiology
Anesthesiology. April 1995: 82(4):954–962.
https://doi.org/10.1097/00000542-199504000-00019
Published: April 1995
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Articles

Central α 1 -Adrenoceptor Stimulation Functionally Antagonizes the Hypnotic Response to Dexmedetomidine, an α 2 -Adrenoceptor Agonist

Tian-Zhi Guo, M.D., Julie Tinkienberg, B.S. (Hon), Rachel Oliker, B.S. (Hon), Mervyn Maze, M.B., Ch.B.
Publication: Anesthesiology
Anesthesiology. August 1991: 75(2):252–256
https://doi.org/10.1097/00000542-199108000-00013
Published: August 1991
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