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Articles

Systematized Serendipity: Fishing Expeditions for Anesthetic Drugs and Targets

C. Michael Crowder, M.D., Ph.D., Stuart A. Forman, M.D., Ph.D.

Anesthesiology. September 2024: 10.1097/ALN.0000000000005153

https://doi.org/10.1097/ALN.0000000000005153

Published: September 2024

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Articles

Repurposing General Anesthetic Drugs to Treat Depression: A New Frontier for Anesthesiologists in Neuropsychiatric Care

Connor T. A. Brenna, M.D., Benjamin I. Goldstein, M.D., Ph.D., Carlos A. Zarate, Jr., M.D., Beverley A. Orser, M.D., Ph.D., F.R.S.C., F.C.A.H.S.

Anesthesiology. August 2024: 141(2):222–237

https://doi.org/10.1097/ALN.0000000000005037

Published: August 2024

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Articles

Discovering the Intriguing Properties of Extrasynaptic γ-Aminobutyric Acid Type A Receptors

Beverley A. Orser, O.Ont., M.D., Ph.D., F.R.S.C., F.C.A.H.S., F.R.C.P.C.

Anesthesiology. June 2024: 140(6):1192–1200

https://doi.org/10.1097/ALN.0000000000004949

Published: June 2024

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Articles

Time to Wake Up! The Ongoing Search for General Anesthetic Reversal Agents

Drew M. Cylinder, Ph.D., André A. J. van Zundert, M.D., Ph.D., Ken Solt, M.D., Bruno van Swinderen, Ph.D.

Anesthesiology. March 2024: 140(3):610–627

https://doi.org/10.1097/ALN.0000000000004846

Published: March 2024

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Articles

Ten Women Who Changed Science and the World

Kathryn Elizabeth McGoldrick, M.D., F.C.A.I. (Hon).

Anesthesiology. November 2022: 137(5):658–659

https://doi.org/10.1097/ALN.0000000000004322

Published: November 2022

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Articles

Anesthesia as Decoupling?

Andrew E. Hudson, M.D., Ph.D.

Anesthesiology. July 2020: 133(1):11–12

https://doi.org/10.1097/ALN.0000000000003366

Published: July 2020

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Articles

Effect of a Cognitive Aid on Reducing Sugammadex Use and Associated Costs: A Time Series Analysis

Dan M. Drzymalski, M.D., Roman Schumann, M.D., Frank J. Massaro, Pharm.D., Agnieszka Trzcinka, M.D., Ruben J. Azocar, M.D.

Anesthesiology. November 2019: 131(5):1036–1045

https://doi.org/10.1097/ALN.0000000000002946

Published: November 2019

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Articles

Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations

Logan J. Voss, Ph.D., Paul S. García, M.D., Ph.D., Harald Hentschke, Ph.D., Matthew I. Banks, Ph.D.

Anesthesiology. June 2019: 130(6):1049–1063

https://doi.org/10.1097/ALN.0000000000002554

Published: June 2019

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Articles

Gone Fishing…

Roderic G. Eckenhoff, M.D.

Anesthesiology. September 2018: 129(3):392–393

https://doi.org/10.1097/ALN.0000000000002328

Published: September 2018

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Articles

Disruption of Hippocampal Multisynaptic Networks by General Anesthetics

Min-Ching Kuo, Ph.D., L. Stan Leung, Ph.D.

Anesthesiology. November 2017: 127(5):838–851

https://doi.org/10.1097/ALN.0000000000001861

Published: November 2017

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Articles

Inflammation Increases Neuronal Sensitivity to General Anesthetics

Sinziana Avramescu, M.D., Ph.D., Dian-Shi Wang, M.D., Ph.D., Irene Lecker, Ph.D., William T. H. To, M.Sc., Antonello Penna, M.D., Ph.D., Paul D. Whissell, Ph.D., Lia Mesbah-Oskui, M.Sc., Richard L. Horner, Ph.D., Beverley A. Orser, M.D., Ph.D.

Anesthesiology. February 2016: 124(2):417–427

https://doi.org/10.1097/ALN.0000000000000943

Published: February 2016

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Articles

The Role of Dendritic Signaling in the Anesthetic Suppression of Consciousness

Kaspar Meyer, M.D.

Anesthesiology. June 2015: 122(6):1415–1431

https://doi.org/10.1097/ALN.0000000000000673

Published: June 2015

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Articles

Discovery of a Novel General Anesthetic Chemotype Using High-throughput Screening

Andrew R. McKinstry-Wu, M.D., Weiming Bu, Ph.D., Ganesha Rai, Ph.D., Wendy A. Lea, Ph.D., Brian P. Weiser, B.S., David F. Liang, B.S., Anton Simeonov, Ph.D., Ajit Jadhav, Ph.D., David J. Maloney, Ph.D., Roderic G. Eckenhoff, M.D.

Anesthesiology. February 2015: 122(2):325–333

https://doi.org/10.1097/ALN.0000000000000505

Published: February 2015

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Articles

General Anesthetic Isoflurane Modulates Inositol 1,4,5-Trisphosphate Receptor Calcium Channel Opening

J. Donald Joseph, Ph.D., Yi Peng, M.D., Don-On Daniel Mak, Ph.D., King-Ho Cheung, Ph.D., Horia Vais, Ph.D., J. Kevin Foskett, Ph.D., Huafeng Wei, M.D., Ph.D.

Anesthesiology. September 2014: 121(3):528–537

https://doi.org/10.1097/ALN.0000000000000316

Published: September 2014

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Articles

Complex Information for Anesthesiologists Presented Quickly and Clearly

Anesthesiology. June 2014: 120(6):A23

https://doi.org/10.1097/01.anes.0000450088.98178.61

Published: June 2014

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Articles

Effects of General Anesthetics on Substance P Release and c-Fos Expression in the Spinal Dorsal Horn

Toshifumi Takasusuki, M.D., Ph.D., Shigeki Yamaguchi, M.D., Ph.D., Shinsuke Hamaguchi, M.D., Ph.D., Tony L. Yaksh, Ph.D.

Anesthesiology. August 2013: 119(2):433–442

https://doi.org/10.1097/ALN.0b013e31829996b6

Published: August 2013

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Articles

Bidirectional Regulation of Intravenous General Anesthetic Actions by α3-containing γ-aminobutyric Acid A Receptors

Carolin J. Straub, Ph.D., Hew Mun Lau, B.Sc., Rosanna Parlato, Ph.D., Guenther Schuetz, M.D., Jean-Marc Fritschy, Ph.D., Uwe Rudolph, M.D.

Anesthesiology. March 2013: 118(3):562–576

https://doi.org/10.1097/ALN.0b013e3182800d76

Published: March 2013

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Articles

A Novel Fluorescent General Anesthetic Enables Imaging of Sites of Action In Vivo

Daniel J. Emerson, B.S., Zhengzheng Liao, B.S., Roderic G. Eckenhoff, M.D., Ivan J. Dmochowski, Ph.D.

Anesthesiology. June 2012: 116(6):1363

https://doi.org/10.1097/ALN.0b013e31824cb4b1

Published: June 2012

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Articles

Exceptionally Stable Fluorous Emulsions for the Intravenous Delivery of Volatile General Anesthetics

Jun-Pil Jee, Ph.D., Maria C. Parlato, Ph.D., Mark G. Perkins, B.S., Sandro Mecozzi, Ph.D., Robert A. Pearce, M.D., Ph.D.

Anesthesiology. March 2012: 116(3):580–585

https://doi.org/10.1097/ALN.0b013e3182475d4d

Published: March 2012

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Articles

Deleterious Impact of a γ-Aminobutyric Acid Type A Receptor Preferring General Anesthetic When Used in the Presence of Persistent Inflammation

Kevin Boegel, B.A., Ferenc E. Gyulai, M.D., Kerry K. Moore, Michael S. Gold, Ph.D.

Anesthesiology. October 2011: 115(4):782–790

https://doi.org/10.1097/ALN.0b013e318215e1cb

Published: October 2011

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NARROW

Systematized Serendipity: Fishing Expeditions for Anesthetic Drugs and Targets

Repurposing General Anesthetic Drugs to Treat Depression: A New Frontier for Anesthesiologists in Neuropsychiatric Care

Discovering the Intriguing Properties of Extrasynaptic γ-Aminobutyric Acid Type A Receptors

Time to Wake Up! The Ongoing Search for General Anesthetic Reversal Agents

Ten Women Who Changed Science and the World

Anesthesia as Decoupling?

Effect of a Cognitive Aid on Reducing Sugammadex Use and Associated Costs: A Time Series Analysis

Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations

Gone Fishing…

Disruption of Hippocampal Multisynaptic Networks by General Anesthetics

Inflammation Increases Neuronal Sensitivity to General Anesthetics

The Role of Dendritic Signaling in the Anesthetic Suppression of Consciousness

Discovery of a Novel General Anesthetic Chemotype Using High-throughput Screening

General Anesthetic Isoflurane Modulates Inositol 1,4,5-Trisphosphate Receptor Calcium Channel Opening

Complex Information for Anesthesiologists Presented Quickly and Clearly

Effects of General Anesthetics on Substance P Release and c-Fos Expression in the Spinal Dorsal Horn

Bidirectional Regulation of Intravenous General Anesthetic Actions by α3-containing γ-aminobutyric Acid A Receptors

A Novel Fluorescent General Anesthetic Enables Imaging of Sites of Action In Vivo

Exceptionally Stable Fluorous Emulsions for the Intravenous Delivery of Volatile General Anesthetics

Deleterious Impact of a γ-Aminobutyric Acid Type A Receptor Preferring General Anesthetic When Used in the Presence of Persistent Inflammation

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