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Increased Postoperative Opioid Consumption in the Presence of Coadministration of 5-Hydroxytryptamine Type 3 Antagonists with Acetaminophen: A Hospital Registry Study

Nikolai Ratajczak, Ricardo Munoz-Acuna, M.D., Simone Redaelli, M.D., Aiman Suleiman, M.D., M.Sc., Eva-Lotte Seibold, Dario von Wedel, Denys Shay, M.D., Sarah Ashrafian, M.Sc., Guanqing Chen, Ph.D., Eswar Sundar, M.B.B.S., Elena Ahrens, Luca J. Wachtendorf, M.D., Maximilian S. Schaefer, M.D., Ph.D.

Anesthesiology. August 2024: 141(2):326–337

https://doi.org/10.1097/ALN.0000000000005033

Published: August 2024

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Articles

Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury

Amie L. Severino, Ph.D., Rong Chen, Ph.D., Kenichiro Hayashida, D.V.M., Ph.D., Carol A. Aschenbrenner, M.A., Haiguo Sun, Ph.D., Christopher M. Peters, Ph.D., Silvia Gutierrez, Ph.D., Bethany Pan, B.S., James C. Eisenach, Ph.D.

Anesthesiology. September 2018: 129(3):544–556

https://doi.org/10.1097/ALN.0000000000002290

Published: September 2018

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Articles

Free Fatty Acid Receptor G-protein–coupled Receptor 40 Mediates Lipid Emulsion-induced Cardioprotection

Soban Umar, M.D., Ph.D., Jingyuan Li, M.D., Ph.D., Kyle Hannabass, M.D., Mylene Vaillancourt, M.Sc., Christine M. Cunningham, B.S., Shayan Moazeni, B.S., Aman Mahajan, M.D., Ph.D., Mansoureh Eghbali, Ph.D.

Anesthesiology. July 2018: 129(1):154–162

https://doi.org/10.1097/ALN.0000000000002195

Published: July 2018

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Articles

Transient Receptor Potential Vanilloid 1 Antagonists Prevent Anesthesia-induced Hypothermia and Decrease Postincisional Opioid Dose Requirements in Rodents

Andras Garami, M.D., Ph.D., Mohab Ibrahim, M.D., Ph.D., Kerry Gilbraith, B.S., Rajesh Khanna, Ph.D., Eszter Pakai, M.S., Alexandra Miko, M.D., Erika Pinter, M.D., Ph.D., D.Sc., Andrej A. Romanovsky, M.D., Ph.D., Frank Porreca, Ph.D., Amol M. Patwardhan, M.D., Ph.D.

Anesthesiology. November 2017: 127(5):813–823

https://doi.org/10.1097/ALN.0000000000001812

Published: November 2017

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Articles

High Concentrations of Tranexamic Acid Inhibit Ionotropic Glutamate Receptors

Irene Lecker, Ph.D., Dian-Shi Wang, M.D., Ph.D., Kirusanthy Kaneshwaran, B.S., C. David Mazer, M.D., Beverley A. Orser, M.D., Ph.D.

Anesthesiology. July 2017: 127(1):89–97

https://doi.org/10.1097/ALN.0000000000001665

Published: July 2017

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Articles

Hypoxia Induces Internalization of κ-Opioid Receptor

Chunhua Xi, M.D., Xuan Liang, M.D., Chunhua Chen, M.D., Ph.D., Hasan Babazada, Ph.D., Tianzuo Li, M.D., Ph.D., Renyu Liu, M.D., Ph.D.

Anesthesiology. May 2017: 126(5):842–854

https://doi.org/10.1097/ALN.0000000000001571

Published: May 2017

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Articles

Opioid-type Respiratory Depressant Side Effects of Cebranopadol in Rats Are Limited by Its Nociceptin/Orphanin FQ Peptide Receptor Agonist Activity

Klaus Linz, Ph.D., Wolfgang Schröder, Ph.D., Stefanie Frosch, Ph.D., Thomas Christoph, Ph.D.

Anesthesiology. April 2017: 126(4):708–715

https://doi.org/10.1097/ALN.0000000000001530

Published: April 2017

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Articles

Proteinase-activated Receptor 1 Contributed to Up-regulation of Enkephalin in Keratinocytes of Patients with Obstructive Jaundice

Kun-Ming Tao, M.B.B.S., Yong Tao, M.B.B.S., Cai-Yang Chen, M.B.B.S., Li-Qun Yang, M.D., Zhi-Jie Lu, M.D., Yu-Ming Sun, M.D., Sheng-Dong Huang, M.D., Ph.D., Wei-Feng Yu, M.D., Ph.D.

Anesthesiology. July 2014: 121(1):127–139

https://doi.org/10.1097/ALN.0000000000000210

Published: July 2014

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Articles

Chemokine (C-C motif) Receptor 5 Is an Important Pathological Regulator in the Development and Maintenance of Neuropathic Pain

Katsuyuki Matsushita, M.D., Hidetoshi Tozaki-Saitoh, Ph.D., Chinami Kojima, B.S., Takahiro Masuda, Ph.D., Makoto Tsuda, Ph.D., Kazuhide Inoue, Ph.D., Sumio Hoka, M.D., Ph.D.

Anesthesiology. June 2014: 120(6):1491–1503

https://doi.org/10.1097/ALN.0000000000000190

Published: June 2014

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Articles

Anesthesia Literature Review

Jean Mantz, M.D., Ph.D.

Anesthesiology. March 2013: 118(3):712–714

https://doi.org/10.1097/ALN.0b013e3182829a0e

Published: March 2013

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Articles

Transient Receptor Potential Ankyrin 1 Ion Channel Contributes to Guarding Pain and Mechanical Hypersensitivity in a Rat Model of Postoperative Pain

Hong Wei, Ph.D., Mari Karimaa, M.Sc., Timo Korjamo, Ph.D., Ari Koivisto, Ph.D., Antti Pertovaara, M.D., Ph.D.

Anesthesiology. July 2012: 117(1):137–148

https://doi.org/10.1097/ALN.0b013e31825adb0e

Published: July 2012

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Articles

Intrathecal Injection of Metabotropic Glutamate Receptor Subtype 3 and 5 Agonist/Antagonist Attenuates Bone Cancer Pain by Inhibition of Spinal Astrocyte Activation in a Mouse Model

Bing-xu Ren, M.D., Ph.D., Xiao-ping Gu, M.D., Ph.D., Ya-guo Zheng, M.D., Cheng-long Liu, M.D., Dan Wang, M.D., Yu-e Sun, M.D., Zheng-liang Ma, M.D., Ph.D.

Anesthesiology. January 2012: 116(1):122–132

https://doi.org/10.1097/ALN.0b013e31823de68d

Published: January 2012

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Articles

Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization-activated Cation Current

Chad M. Brummett, M.D., Elizabeth K. Hong, B.S., Allison M. Janda, B.A., Francesco S. Amodeo, B.S., Ralph Lydic, Ph.D.

Anesthesiology. October 2011: 115(4):836–843

https://doi.org/10.1097/ALN.0b013e318221fcc9

Published: October 2011

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Articles

Nonselective and NR2B-selective N -methyl-d-aspartic Acid Receptor Antagonists Produce Antinociception and Long-term Relief of Allodynia in Acute and Neuropathic Pain

Maarten Swartjes, B.Sc., Aurora Morariu, M.D., Ph.D., Marieke Niesters, M.D., M.Sc., Leon Aarts, M.D., Ph.D., Albert Dahan, M.D., Ph.D.

Anesthesiology. July 2011: 115(1):165–174

https://doi.org/10.1097/ALN.0b013e31821bdb9b

Published: July 2011

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Articles

Pulmonary Vasoconstrictive and Bronchoconstrictive Responses to Anaphylaxis Are Weakened via β 2 -adrenoceptor Activation by Endogenous Epinephrine in Anesthetized Rats

Wei Zhang, M.Sc., Toshishige Shibamoto, M.D., Ph.D., Yuhichi Kuda, B.Sc., Chieko Ohmukai, B.Sc., Yasutaka Kurata, M.D., Ph.D.

Anesthesiology. March 2011: 114(3):614–623

https://doi.org/10.1097/ALN.0b013e31820b8d34

Published: March 2011

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Articles

Salvinorin A Produces Cerebrovasodilation through Activation of Nitric Oxide Synthase, κ Receptor, and Adenosine Triphosphate–sensitive Potassium Channel

Diansan Su, M.D., Ph.D., John Riley, B.A., Willis J. Kiessling, B.A., William M. Armstead, Ph.D., Renyu Liu, M.D., Ph.D.

Anesthesiology. February 2011: 114(2):374–379

https://doi.org/10.1097/ALN.0b013e318204e029

Published: February 2011

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Articles

Anesthesia Literature Review

Timothy J. Brennan, Ph.D., M.D.

Anesthesiology. December 2010: 113(6):1448–1452

https://doi.org/10.1097/ALN.0b013e3181fc252d

Published: December 2010

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Articles

Perioperative Use of β-Adrenergic Antagonists and Anemia: Known Knowns, Known Unknowns, Unknown Unknowns; and Unknown Knowns

Richard B. Weiskopf, M.D.

Anesthesiology. January 2010: 112(1):12–15

https://doi.org/10.1097/ALN.0b013e3181c5dc18

Published: January 2010

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Articles

Attenuation of Mechanical Hypersensitivity by an Antagonist of the TRPA1 Ion Channel in Diabetic Animals

Hong Wei, Ph.D., Minna M. Hämäläinen, Ph.D., Marja Saarnilehto, M.Sc., Ari Koivisto, Ph.D., Antti Pertovaara, M.D., Ph.D.

Anesthesiology. July 2009: 111(1):147–154

https://doi.org/10.1097/ALN.0b013e3181a1642b

Published: July 2009

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Articles

Intrathecal Injection of the ς 1 Receptor Antagonist BD1047 Blocks Both Mechanical Allodynia and Increases in Spinal NR1 Expression during the Induction Phase of Rodent Neuropathic Pain

Dae-Hyun Roh, D.V.M., M.S., Hyun-Woo Kim, D.V.M., Ph.D., Seo-Yeon Yoon, D.V.M., Ph.D., Hyoung-Sig Seo, D.V.M., M.S., Young-Bae Kwon, D.V.M., Ph.D., Kee-Won Kim, M.D., Ph.D., Ho-Jae Han, D.V.M., Ph.D., Alvin J. Beitz, Ph.D., Heung-Sik Na, M.D., Ph.D., Jang-Hern Lee, D.V.M., Ph.D.

Anesthesiology. November 2008: 109(5):879–889

https://doi.org/10.1097/ALN.0b013e3181895a83

Published: November 2008

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NARROW

Increased Postoperative Opioid Consumption in the Presence of Coadministration of 5-Hydroxytryptamine Type 3 Antagonists with Acetaminophen: A Hospital Registry Study

Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury

Free Fatty Acid Receptor G-protein–coupled Receptor 40 Mediates Lipid Emulsion-induced Cardioprotection

Transient Receptor Potential Vanilloid 1 Antagonists Prevent Anesthesia-induced Hypothermia and Decrease Postincisional Opioid Dose Requirements in Rodents

High Concentrations of Tranexamic Acid Inhibit Ionotropic Glutamate Receptors

Hypoxia Induces Internalization of κ-Opioid Receptor

Opioid-type Respiratory Depressant Side Effects of Cebranopadol in Rats Are Limited by Its Nociceptin/Orphanin FQ Peptide Receptor Agonist Activity

Proteinase-activated Receptor 1 Contributed to Up-regulation of Enkephalin in Keratinocytes of Patients with Obstructive Jaundice

Chemokine (C-C motif) Receptor 5 Is an Important Pathological Regulator in the Development and Maintenance of Neuropathic Pain

Anesthesia Literature Review

Transient Receptor Potential Ankyrin 1 Ion Channel Contributes to Guarding Pain and Mechanical Hypersensitivity in a Rat Model of Postoperative Pain

Intrathecal Injection of Metabotropic Glutamate Receptor Subtype 3 and 5 Agonist/Antagonist Attenuates Bone Cancer Pain by Inhibition of Spinal Astrocyte Activation in a Mouse Model

Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization-activated Cation Current

Nonselective and NR2B-selective N -methyl-d-aspartic Acid Receptor Antagonists Produce Antinociception and Long-term Relief of Allodynia in Acute and Neuropathic Pain

Pulmonary Vasoconstrictive and Bronchoconstrictive Responses to Anaphylaxis Are Weakened via β 2 -adrenoceptor Activation by Endogenous Epinephrine in Anesthetized Rats

Salvinorin A Produces Cerebrovasodilation through Activation of Nitric Oxide Synthase, κ Receptor, and Adenosine Triphosphate–sensitive Potassium Channel

Anesthesia Literature Review

Perioperative Use of β-Adrenergic Antagonists and Anemia: Known Knowns, Known Unknowns, Unknown Unknowns; and Unknown Knowns

Attenuation of Mechanical Hypersensitivity by an Antagonist of the TRPA1 Ion Channel in Diabetic Animals

Intrathecal Injection of the ς 1 Receptor Antagonist BD1047 Blocks Both Mechanical Allodynia and Increases in Spinal NR1 Expression during the Induction Phase of Rodent Neuropathic Pain

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