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Articles

Stereoselective Ketamine Metabolism by Genetic Variants of Cytochrome P450 CYP2B6 and Cytochrome P450 Oxidoreductase

Pan-Fen Wang, Ph.D., Alicia Neiner, Evan D. Kharasch, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. October 2018: 129(4):756–768
https://doi.org/10.1097/ALN.0000000000002371
Published: October 2018
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Room H, 10/16/2000 9: 00 AM - 11: 00 AM (PS) The α-Helical Membrane Spanning Domains of Cytochrome P450 and Cytochrome b 5 Bind Via Nonspecific Hydrophobic Interactions  : A-543

Lucy A. Waskell, M.D.,Ph.D., Scott B. Mulrooney, Ph.D., David R. Meinhardt, Student
Publication: Anesthesiology
Anesthesiology. September 2000: 93(3A):A–543
https://doi.org/10.1097/00000542-200009001-00543
Published: September 2000
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Propofol Attenuates Acetylcholine-induced Pulmonary Vasorelaxation: Role of Nitric Oxide and Endothelium-derived Hyperpolarizing Factors

Mayumi Horibe, M.D., Koji Ogawa, M.D., Ju-Tae Sohn, M.D., Paul A. Murray, Ph.D.
Publication: Anesthesiology
Anesthesiology. August 2000: 93(2):447–455
https://doi.org/10.1097/00000542-200008000-00024
Published: August 2000
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Pharmacokinetics and Pharmacodynamics of Vecuronium in Rats with Systemic Inflammatory Response Syndrome   : Treatment with NG-Monomethyl-L-Arginine

Manfred Blobner, M.D., Eberhard Kochs, M.D., M.Sc., Heidrun Fink, M.D., Barbara Mayer, M.D., Andreas Veihelmann, M.D., Thomas Brill, M.D., D.V.M., Josef Stadler, M.D.
Publication: Anesthesiology
Anesthesiology. October 1999: 91(4):999
https://doi.org/10.1097/00000542-199910000-00020
Published: October 1999
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Clinical Isoflurane Metabolism by Cytochrome P450 2E1

Evan D. Kharasch, MD, PhD, Douglas C. Hankins, MA, Kathy Cox, BS
Publication: Anesthesiology
Anesthesiology. March 1999: 90(3):766–771
https://doi.org/10.1097/00000542-199903000-00019
Published: March 1999
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The Role of Cytochrome P450 3A4 in Alfentanil Clearance   : Implications for Interindividual Variability in Disposition and Perioperative Drug Interactions

Evan D. Kharasch, MD, PhD, Michael Russell, MD, PhD, Douglas Mautz, PhD, Kenneth E. Thummel, PhD, Kent L. Kunze, PhD, T. Andrew Bowdle, MD, PhD, Kathy Cox, BS
Publication: Anesthesiology
Anesthesiology. July 1997: 87(1):36–50
https://doi.org/10.1097/00000542-199707000-00006
Published: July 1997
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Nitric Oxide Mediates Hepatic Cytochrome P450 Dysfunction Induced by Endotoxin

Claudia M. Muller, MD, Annette Scierka, MS, Richard L. Stiller, PhD, Yong-Myeong Kim, PhD, Ryan D. Cook, MD, Jack R. Lancaster, PhD, Charles W. Buffington, MD, David W. Watkins, MD, PhD
Publication: Anesthesiology
Anesthesiology. June 1996: 84(6):1435–1442
https://doi.org/10.1097/00000542-199606000-00020
Published: June 1996
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Inhalation Anesthetics Inhibit the Release of Endothelium-derived Hyperpolarizing Factor in the Rabbit Carotid Artery

Volker Lischke, MD, Rudi Busse, MD, PhD, Markus Hecker, PhD
Publication: Anesthesiology
Anesthesiology. September 1995: 83(3):574–582.
https://doi.org/10.1097/00000542-199509000-00017
Published: September 1995
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Clinical Sevoflurane Metabolism and Disposition: II. The Role of Cytochrome P450 2E1 in Fluoride and Hexafluoroisopropanol Formation

Evan D. Kharasch, MD, PhD, Andrew S. Armstrong, MBBS, FANZCA, Kerry Gunn, MBChB, FANZCA, Alan Artru, MD, Kathy Cox, BS, Michael D. Karol, PhD
Publication: Anesthesiology
Anesthesiology. June 1995: 82(6):1379–1388.
https://doi.org/10.1097/00000542-199506000-00009
Published: June 1995
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Human Kidney Methoxyflurane and Sevoflurane Metabolism   : Intrarenal Fluoride Production as a Possible Mechanism of Methoxyflurane Nephrotoxicity

Evan D. Kharasch, MD, PhD, Douglas C. Hankins, MA, Kenneth E. Thummel, PhD
Publication: Anesthesiology
Anesthesiology. March 1995: 82(3):689–699
https://doi.org/10.1097/00000542-199503000-00011
Published: March 1995
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Metabolism of a New Local Anesthetic, Ropivacaine, by Human Hepatic Cytochrome P450

Yutaka Oda, MD, Katsuji Furuichi, MD, Kazuo Tanaka, MD, Toyoko Hiroi, Susumu Imaoka, PhD, Akira Asada, MD, Mitsugu Fujimori, MD, Yoshihiko Funae, PhD
Publication: Anesthesiology
Anesthesiology. January 1995: 82(1):214–220
https://doi.org/10.1097/00000542-199501000-00026
Published: January 1995
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Identification of the Pharmacogenetic Determinants of Alfentanil Metabolism: Cytochrome P-450 3A4 An Explanation of the Variable Elimination Clearance

Chul-Ho Yun, Ph.D., Margaret Wood, M.B.Ch.B., F.F.A.R.C.S., Alastair J. J. Wood, M.B.Ch.B., F.R.C.P.(Edin), F. Peter Guengerich, Ph.D.
Publication: Anesthesiology
Anesthesiology. September 1992: 77(3):467–474
https://doi.org/10.1097/00000542-199209000-00011
Published: September 1992
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EFFECTS OF NITRIC OXIDE ON THE METABOLIC ACTIVITY OF HEPATIC CYTOCHROME P450

E. Masaki, M.D., H.M. Marsh, M. B. B. S., R.A. Van Dyke, PhD.
Publication: Anesthesiology
Anesthesiology. September 1992: 77(3A Supplement):A442
Published: September 1992
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A396 RELATIONSHIP BETWEEN SERUM F“ AND CYTOCHROME P-450 AFTER EVOFLURANE ANESTHESIA IN ETHANOL TREATED RATS

E. Masaki, M.D, T. Kondou, M.D, K. Kobayashi, M.D.
Publication: Anesthesiology
Anesthesiology. September 1990: 73(3A):NA
https://doi.org/10.1097/00000542-199009001-00393
Published: September 1990
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Interaction of Volatile Anesthetics with Rat Hepatic Microsomal Cytochrome P-450

S. Takahashi, M.D., A. Shigematsu, M.D., T. Furukawa, M.D.
Publication: Anesthesiology
Anesthesiology. October 1974: 41(4):375–379
https://doi.org/10.1097/00000542-197410000-00012
Published: October 1974
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