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Spinal Anesthesia with Targeted Sedation based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium: The SHARP Randomized Controlled Trial

This article has a Visual Abstract This article has an Audio Podcast
Charles H. Brown, IV, M.D., M.H.S., Charles Edwards, II, M.D., Charles Lin, M.D., Emily Ledford Jones, M.S., R.N., C.N.L., Lisa R. Yanek, M.P.H., Melody Esmaili, C.R.N.A., Yara Gorashi, B.A., Richard Skelton, B.S., M.H.S., Daniel Kaganov, B.A., Ryan Curto, B.A., Noah L. Lessing, B.S., Stephanie Cha, M.D., Elizabeth Colantuoni, Ph.D., Karin Neufeld, M.D., M.P.H., Frederick Sieber, M.D., Clayton L. Dean, M.D., Charles W. Hogue, M.D.
Publication: Anesthesiology
Anesthesiology. December 2021: 135(6):992–1003
DOI: https://doi.org/10.1097/ALN.0000000000004015
Published: December 2021
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Sleep, Pain, and Cognition: Modifiable Targets for Optimal Perioperative Brain Health

CME Article
Brian P. O’Gara, M.D., M.P.H., Lei Gao, M.D., M.B.B.S., Edward R. Marcantonio, M.D., Balachundhar Subramaniam, M.D., M.P.H., F.A.S.A.
Publication: Anesthesiology
Anesthesiology. December 2021: 135(6):1132–1152
DOI: https://doi.org/10.1097/ALN.0000000000004046
Published: December 2021
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Delirium in Older Patients after Combined Epidural–General Anesthesia or General Anesthesia for Major Surgery: A Randomized Trial

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Ya-Wei Li, M.D., Huai-Jin Li, M.D., Hui-Juan Li, Ph.D., Bin-Jiang Zhao, M.D., Xiang-Yang Guo, M.D., Yi Feng, M.D., Ming-Zhang Zuo, M.D., Yong-Pei Yu, Ph.D., Hao Kong, M.D., Yi Zhao, M.D., Da Huang, M.D., Chun-Mei Deng, M.D., Xiao-Yun Hu, M.D., Peng-Fei Liu, M.D., Yan Li, M.D., Hai-Yan An, M.D., Hong-Ye Zhang, M.D., Mei-Rong Wang, M.D., Yang-Feng Wu, M.D., Ph.D., Dong-Xin Wang, M.D., Ph.D., Daniel I. Sessler, M.D., for the Peking University Clinical Research Program Study Group
Publication: Anesthesiology
Anesthesiology. August 2021: 135(2):218–232
DOI: https://doi.org/10.1097/ALN.0000000000003834
Published: August 2021
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The Cognitive Neuraxis: Epidurals and Postoperative Delirium

Phillip E. Vlisides, M.D., George A. Mashour, M.D., Ph.D.
Publication: Anesthesiology
Anesthesiology. August 2021: 135(2):197–199
DOI: https://doi.org/10.1097/ALN.0000000000003824
Published: August 2021
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Putting the Neuro in Neuraxial: Delirium Reduction and Epidurals

Jonathan P. Wanderer, James P. Rathmell
Publication: Anesthesiology
Anesthesiology. August 2021: 135(2):A19
DOI: https://doi.org/10.1097/ALN.0000000000003892
Published: August 2021
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Brief Preoperative Screening for Frailty and Cognitive Impairment Predicts Delirium after Spine Surgery

Maria J. Susano, M.D., Rachel H. Grasfield, B.A., Matthew Friese, M.D., Ph.D., Bernard Rosner, Ph.D., Gregory Crosby, M.D., Angela M. Bader, M.D., James D. Kang, M.D., Timothy R. Smith, M.D., Ph.D., Yi Lu, M.D., Ph.D., F.A.A.N.S., Michael W. Groff, M.D., John H. Chi, M.D., M.P.H., Francine Grodstein, Ph.D., Deborah J. Culley, M.D.
Publication: Anesthesiology
Anesthesiology. December 2020: 133(6):1184–1191
DOI: https://doi.org/10.1097/ALN.0000000000003523
Published: December 2020
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Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium

Juan C. Pedemonte, M.D., George S. Plummer, M.D., Shubham Chamadia, Ph.D., Joseph J. Locascio, Ph.D., Eunice Hahm, B.S., Breanna Ethridge, B.A., Jacob Gitlin, B.S., Reine Ibala, B.S., Jennifer Mekonnen, B.S., Katia M. Colon, B.S., M. Brandon Westover, M.D., Ph.D., David A. D’Alessandro, M.D., George Tolis, M.D., Timothy Houle, Ph.D., Kenneth T. Shelton, M.D., Jason Qu, M.D., Oluwaseun Akeju, M.D., M.M.S.C.I.
Publication: Anesthesiology
Anesthesiology. August 2020: 133(2):280–292
DOI: https://doi.org/10.1097/ALN.0000000000003328
Published: August 2020
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Association between Use of Angiotensin-converting Enzyme Inhibitors or Angiotensin Receptor Blockers and Postoperative Delirium

Ehab Farag, M.D., F.R.C.A., F.A.S.A., Chen Liang, M.S., Edward J. Mascha, Ph.D., Maged Y. Argalious, M.D., M.Sc., M.B.A., M.Ed., F.A.S.E., F.A.S.A., Jacob Ezell, M.D., Kamal Maheshwari, M.D., M.P.H., Wael Ali Sakr Esa, M.D., Ph.D., M.B.A., Christopher A. Troianos, M.D., F.A.S.E., F.A.S.A., Daniel I. Sessler, M.D.
Publication: Anesthesiology
Anesthesiology. July 2020: 133(1):119–132
DOI: https://doi.org/10.1097/ALN.0000000000003329
Published: July 2020
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Preoperative Cognitive Abnormality, Intraoperative Electroencephalogram Suppression, and Postoperative Delirium: A Mediation Analysis

Bradley A. Fritz, M.D., Christopher R. King, M.D., Ph.D., Arbi Ben Abdallah, Ph.D., Nan Lin, Ph.D., Angela M. Mickle, M.S., Thaddeus P. Budelier, M.D., M.S.F., Jordan Oberhaus, B.S., Daniel Park, B.S., Hannah R. Maybrier, B.S., Troy S. Wildes, M.D., Michael S. Avidan, M.B.B.Ch., for the ENGAGES Research Group*
Publication: Anesthesiology
Anesthesiology. June 2020: 132(6):1458–1468
DOI: https://doi.org/10.1097/ALN.0000000000003181
Published: June 2020
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Oxidative Stress Response and Delirium after Cardiac Surgery: Can Circulating Biomarkers Refine New Therapeutic Paradigms?

Mihai V. Podgoreanu, M.D., Michael J. Devinney, Jr., M.D., Ph.D., Joseph P. Mathew, M.D., M.H.Sc., M.B.A.
Publication: Anesthesiology
Anesthesiology. March 2020: 132(3):418–420
DOI: https://doi.org/10.1097/ALN.0000000000003097
Published: March 2020
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Intraoperative Oxidative Damage and Delirium after Cardiac Surgery

Marcos G. Lopez, M.D., M.S., Christopher G. Hughes, M.D., M.S., Anthony DeMatteo, B.S., Jason B. O’Neal, M.D., J. Brennan McNeil, B.S., Matthew S. Shotwell, Ph.D., Jennifer Morse, M.S., Michael R. Petracek, M.D., Ashish S. Shah, M.D., Nancy J. Brown, M.D., Frederic T. Billings, IV, M.D., M.Sc.
Publication: Anesthesiology
Anesthesiology. March 2020: 132(3):551–561
DOI: https://doi.org/10.1097/ALN.0000000000003016
Published: March 2020
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Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence

Lori A. Daiello, Pharm.D., Sc.M., Annie M. Racine, Ph.D., Ray Yun Gou, Ph.D., Edward R. Marcantonio, M.D., Zhongcong Xie, M.D., Ph.D., Lisa J. Kunze, M.D., Kamen V. Vlassakov, M.D., Sharon K. Inouye, M.D., Richard N. Jones, Sc.D., for the SAGES Study Group
Publication: Anesthesiology
Anesthesiology. September 2019: 131(3):477–491
DOI: https://doi.org/10.1097/ALN.0000000000002729
Published: September 2019
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Prophylactic Haloperidol Effects on Long-term Quality of Life in Critically Ill Patients at High Risk for Delirium: Results of the REDUCE Study

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Paul J. T. Rood, R.N., M.Sc., Marieke Zegers, Ph.D., Arjen J. C. Slooter, M.D., Ph.D., Albert Beishuizen, M.D., Ph.D., Koen S. Simons, M.D., Ph.D., Peter H. J. van der Voort, M.D., Ph.D., Meta C. E. van der Woude, M.D., Peter E. Spronk, M.D., Ph.D., Johannes G. van der Hoeven, M.D., Ph.D., Peter Pickkers, M.D., Ph.D., Mark van den Boogaard, R.N., Ph.D.
Publication: Anesthesiology
Anesthesiology. August 2019: 131(2):328–335
DOI: https://doi.org/10.1097/ALN.0000000000002812
Published: August 2019
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Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery—2018

L. Evered, B. Silbert, D. S. Knopman, D. A. Scott, S. T. DeKosky, L. S. Rasmussen, E. S. Oh, G. Crosby, M. Berger, R. G. Eckenhoff, The Nomenclature Consensus Working Group
Publication: Anesthesiology
Anesthesiology. November 2018: 129(5):872–879
DOI: https://doi.org/10.1097/ALN.0000000000002334
Published: November 2018
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Neurocognitive Function after Cardiac Surgery: From Phenotypes to Mechanisms

Miles Berger, M.D., Ph.D., Niccolò Terrando, Ph.D., S. Kendall Smith, M.D., Ph.D., Jeffrey N. Browndyke, Ph.D., Mark F. Newman, M.D., Joseph P. Mathew, M.D., M.H.Sc., M.B.A.
Publication: Anesthesiology
Anesthesiology. October 2018: 129(4):829–851
DOI: https://doi.org/10.1097/ALN.0000000000002194
Published: October 2018
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Cognitive Decline after Delirium in Patients Undergoing Cardiac Surgery

Charles H. Brown, IV, M.D., M.H.S., Julia Probert, B.A., Ryan Healy, B.A., Michelle Parish, B.A., Yohei Nomura, M.D., Atsushi Yamaguchi, M.D., Ph.D., Jing Tian, M.S., Kenton Zehr, M.D., Kaushik Mandal, M.D., Vidyulata Kamath, Ph.D., Karin J. Neufeld, M.D., M.P.H., Charles W. Hogue, M.D.
Publication: Anesthesiology
Anesthesiology. September 2018: 129(3):406–416
DOI: https://doi.org/10.1097/ALN.0000000000002253
Published: September 2018
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Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial

Jacqueline M. Leung, M.D., M.P.H., Laura P. Sands, Ph.D., Ningning Chen, Ph.D., Christopher Ames, M.D., Sigurd Berven, M.D., Kevin Bozic, M.D., Shane Burch, M.D., Dean Chou, M.D., Kenneth Covinsky, M.D., Vedat Deviren, M.D., Sakura Kinjo, M.D., Joel H. Kramer, Psy.D., Michael Ries, M.D., Bobby Tay, M.D., Thomas Vail, M.D., Philip Weinstein, M.D., the Perioperative Medicine Research Group
Publication: Anesthesiology
Anesthesiology. October 2017: 127(4):633–644
DOI: https://doi.org/10.1097/ALN.0000000000001804
Published: October 2017
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Investigation of Slow-wave Activity Saturation during Surgical Anesthesia Reveals a Signature of Neural Inertia in Humans

Catherine E. Warnaby, Ph.D., Jamie W. Sleigh, M.D., Darren Hight, B.Sc., Saad Jbabdi, Ph.D., Irene Tracey, M.A., D.Phil., F.R.C.A., F.Med.Sci.
Publication: Anesthesiology
Anesthesiology. October 2017: 127(4):645–657
DOI: https://doi.org/10.1097/ALN.0000000000001759
Published: October 2017
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A Systematic Review and Meta-analysis Examining the Impact of Incident Postoperative Delirium on Mortality

Gavin M. Hamilton, M.D., M.Sc., Kathleen Wheeler, M.D., B.Sc., Joseph Di Michele, B.H.Sc., Manoj M. Lalu, M.D., Ph.D., Daniel I. McIsaac, M.D., M.P.H.
Publication: Anesthesiology
Anesthesiology. July 2017: 127(1):78–88
DOI: https://doi.org/10.1097/ALN.0000000000001660
Published: July 2017
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Impact of Methylprednisolone on Postoperative Quality of Recovery and Delirium in the Steroids in Cardiac Surgery Trial: A Randomized, Double-blind, Placebo-controlled Substudy

Colin F. Royse, M.B.B.S., M.D., F.A.N.Z.C.A., Leif Saager, Dr. med., M.M.M., F.C.C.M., Richard Whitlock, M.D., Ph.D., F.R.C.S.C., Jared Ou-Young, B.Sc., Alistair Royse, M.B.B.S., M.D., F.R.A.C.S., F.C.S.A.N.Z., Jessica Vincent, M.Sc., P. J. Devereaux, M.D., Ph.D., F.R.C.P.C., Andrea Kurz, M.D., Ahmed Awais, M.D., Krit Panjasawatwong, M.D., Daniel I. Sessler, M.D.
Publication: Anesthesiology
Anesthesiology. February 2017: 126(2):223–233
DOI: https://doi.org/10.1097/ALN.0000000000001433
Published: February 2017
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