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Early Fibrinogen Replacement to Treat the Endotheliopathy of Trauma: Novel Resuscitation Strategies in Severe Trauma

David J. Douin, M.D., Ana Fernandez-Bustamante, M.D., Ph.D., F.A.S.A.

Anesthesiology. November 2023: 139(5):675–683

https://doi.org/10.1097/ALN.0000000000004711

Published: November 2023

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Articles

Coagulopathy Underlying Rotational Thromboelastometry Derangements in Trauma Patients: A Prospective Observational Multicenter Study

Romein W. G. Dujardin, M.D., Derek J. B. Kleinveld, Ph.D., Christine Gaarder, Ph.D., Karim Brohi, M.D., Ross A. Davenport, Ph.D., Nicola Curry, M.D., Simon Stanworth, Ph.D., Pär I. Johansson, Ph.D., Jakob Stensballe, Ph.D., Marc Maegele, Ph.D., Nicole P. Juffermans, Ph.D.

Anesthesiology. August 2022: 137(2):232–242

https://doi.org/10.1097/ALN.0000000000004268

Published: August 2022

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Articles

Reversing Rivaroxaban Anticoagulation as Part of a Multimodal Hemostatic Intervention in a Polytrauma Animal Model

Farahnaz Rayatdoost, M.Sc., Till Braunschweig, M.D., Benjamin Maron, M.D., Herbert Schöchl, M.D., Necib Akman, M.D., Rolf Rossaint, M.D., Eva Herzog, Ph.D., Stefan Heitmeier, Ph.D., Oliver Grottke, M.D., Ph.D., M.Sc.

Anesthesiology. October 2021: 135(4):673–685

https://doi.org/10.1097/ALN.0000000000003899

Published: October 2021

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Articles

Viscoelastic Coagulation Testing: Use and Current Limitations in Perioperative Decision-making

Gabor Erdoes, M.D., Ph.D., Andreas Koster, M.D., Ph.D., Jerrold H. Levy, M.D., F.C.C.M.

Anesthesiology. August 2021: 135(2):342–349

https://doi.org/10.1097/ALN.0000000000003814

Published: August 2021

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Articles

Positive Regulatory Domain I–binding Factor 1 Mediates Peripheral Nerve Injury–induced Nociception in Mice by Repressing Kv4.3 Channel Expression

Cunjin Wang, M.D., Ph.D., Yuchen Pan, M.D., Wenwen Zhang, Ph.D., Ying Chen, Ph.D., Chuhan Li, B.S., Fang Zhao, Ph.D., Thomas Behnisch, Ph.D.

Anesthesiology. March 2021: 134(3):435–456

https://doi.org/10.1097/ALN.0000000000003654

Published: March 2021

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Articles

Comparison of Neonatal and Adult Fibrin Clot Properties between Porcine and Human Plasma

Kimberly A. Nellenbach, B.S., Seema Nandi, B.S., Alexander Kyu, Supriya Sivadanam, B.S., Nina A. Guzzetta, M.D., F.A.A.P., Ashley C. Brown, Ph.D.

Anesthesiology. May 2020: 132(5):1091–1101

https://doi.org/10.1097/ALN.0000000000003165

Published: May 2020

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Articles

Prothrombin Complex Concentrate-induced Disseminated Intravascular Coagulation Can Be Prevented by Coadministering Antithrombin in a Porcine Trauma Model

Oliver Grottke, M.D., Ph.D., Markus Honickel, M.D., Till Braunschweig, M.D., Anne Reichel, M.D., Herbert Schöchl, M.D., Rolf Rossaint, M.D.

Anesthesiology. September 2019: 131(3):543–554

https://doi.org/10.1097/ALN.0000000000002797

Published: September 2019

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Articles

Reversing Dabigatran Anticoagulation with Prothrombin Complex Concentrate versus Idarucizumab as Part of Multimodal Hemostatic Intervention in an Animal Model of Polytrauma

Markus Honickel, M.D., Till Braunschweig, M.D., Rolf Rossaint, M.D., Christian Stoppe, M.D., Hugo ten Cate, M.D., Ph.D., Oliver Grottke, M.D., Ph.D.

Anesthesiology. November 2017: 127(5):852–861

https://doi.org/10.1097/ALN.0000000000001856

Published: November 2017

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Articles

Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy

Ross A. Davenport, Ph.D., Maria Guerreiro, M.D., Daniel Frith, Ph.D., Claire Rourke, B.Sc., Sean Platton, B.Sc., Mitchell Cohen, M.D., Rupert Pearse, Ph.D., Chris Thiemermann, Ph.D., Karim Brohi, M.D.

Anesthesiology. January 2017: 126(1):115–127

https://doi.org/10.1097/ALN.0000000000001428

Published: January 2017

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Articles

Fibrinogen Concentrate Does Not Suppress Endogenous Fibrinogen Synthesis in a 24-hour Porcine Trauma Model

Christian Zentai, M.D., Till Braunschweig, M.D., Jonas Schnabel, M.D., Michael Rose, Ph.D., Rolf Rossaint, M.D., Oliver Grottke, M.D., Ph.D.

Anesthesiology. October 2014: 121(4):753–764

https://doi.org/10.1097/ALN.0000000000000315

Published: October 2014

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Articles

Case Scenario: Management of Trauma-induced Coagulopathy in a Severe Blunt Trauma Patient

Jean-Stephane David, M.D., Ph.D., Anne Godier, M.D., Ph.D., Yesim Dargaud, M.D., Ph.D., Kenji Inaba, M.D., M.Sc.

Anesthesiology. July 2013: 119(1):191–200

https://doi.org/10.1097/ALN.0b013e31828fc627

Published: July 2013

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Articles

Effects of Fibrinogen Concentrate as First-line Therapy during Major Aortic Replacement Surgery: A Randomized, Placebo-controlled Trial

Niels Rahe-Meyer, M.D., Ph.D., Cristina Solomon, M.D., Alexander Hanke, M.D., Dirk S. Schmidt, Ph.D., Dietrich Knoerzer, Ph.D., Gerald Hochleitner, Benny Sørensen, M.D., Ph.D., Christian Hagl, M.D., Maximilian Pichlmaier, M.D.

Anesthesiology. January 2013: 118(1):40–50

https://doi.org/10.1097/ALN.0b013e3182715d4d

Published: January 2013

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Articles

Fibrinogen Concentrate and Allogeneic Blood Transfusion in High-risk Surgery

Nauder Faraday, M.D., M.P.H.

Anesthesiology. January 2013: 118(1):7–9

https://doi.org/10.1097/ALN.0b013e3182715d6c

Published: January 2013

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Articles

First-line Therapy with Coagulation Factor Concentrates Combined with Point-of-Care Coagulation Testing Is Associated with Decreased Allogeneic Blood Transfusion in Cardiovascular Surgery: A Retrospective, Single-center Cohort Study

Klaus Görlinger, Dr. med, Daniel Dirkmann, Dr. med, Alexander A. Hanke, Dr. med, Markus Kamler, PD Dr. med, Eva Kottenberg, PD Dr. med, Matthias Thielmann, PD Dr. med, Heinz Jakob, Prof. Dr. med, Jürgen Peters, Prof. Dr. med

Anesthesiology. December 2011: 115(6):1179–1191

https://doi.org/10.1097/ALN.0b013e31823497dd

Published: December 2011

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Articles

Pathophysiology and Treatment of Coagulopathy in Massive Hemorrhage and Hemodilution

Daniel Bolliger, M.D., Klaus Görlinger, M.D., Kenichi A. Tanaka, M.D., M.Sc., David S. Warner, M.D.

Anesthesiology. November 2010: 113(5):1205–1219

https://doi.org/10.1097/ALN.0b013e3181f22b5a

Published: November 2010

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Articles

In Vitro Hypothermia Enhances Platelet GPIIb-IIIa Activation and P-Selectin Expression

Nauder Faraday, MD, Brian Rosenfeld, A., MD

Anesthesiology. June 1998: 88(6):1579–1585

https://doi.org/10.1097/00000542-199806000-00022

Published: June 1998

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Articles

FIBRINOGEN-HEPATITIS RISK

Anesthesiology. January 1967: 28(1):292

https://doi.org/10.1097/00000542-196701000-00136

Published: January 1967

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Articles

THROMBIN–FIBRINOGEN INTERACTION

Anesthesiology. March 1959: 20(2):231

https://doi.org/10.1097/00000542-195903000-00053

Published: March 1959

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NARROW

Early Fibrinogen Replacement to Treat the Endotheliopathy of Trauma: Novel Resuscitation Strategies in Severe Trauma

Coagulopathy Underlying Rotational Thromboelastometry Derangements in Trauma Patients: A Prospective Observational Multicenter Study

Reversing Rivaroxaban Anticoagulation as Part of a Multimodal Hemostatic Intervention in a Polytrauma Animal Model

Viscoelastic Coagulation Testing: Use and Current Limitations in Perioperative Decision-making

Positive Regulatory Domain I–binding Factor 1 Mediates Peripheral Nerve Injury–induced Nociception in Mice by Repressing Kv4.3 Channel Expression

Comparison of Neonatal and Adult Fibrin Clot Properties between Porcine and Human Plasma

Prothrombin Complex Concentrate-induced Disseminated Intravascular Coagulation Can Be Prevented by Coadministering Antithrombin in a Porcine Trauma Model

Reversing Dabigatran Anticoagulation with Prothrombin Complex Concentrate versus Idarucizumab as Part of Multimodal Hemostatic Intervention in an Animal Model of Polytrauma

Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy

Fibrinogen Concentrate Does Not Suppress Endogenous Fibrinogen Synthesis in a 24-hour Porcine Trauma Model

Case Scenario: Management of Trauma-induced Coagulopathy in a Severe Blunt Trauma Patient

Effects of Fibrinogen Concentrate as First-line Therapy during Major Aortic Replacement Surgery: A Randomized, Placebo-controlled Trial

Fibrinogen Concentrate and Allogeneic Blood Transfusion in High-risk Surgery

First-line Therapy with Coagulation Factor Concentrates Combined with Point-of-Care Coagulation Testing Is Associated with Decreased Allogeneic Blood Transfusion in Cardiovascular Surgery: A Retrospective, Single-center Cohort Study

Pathophysiology and Treatment of Coagulopathy in Massive Hemorrhage and Hemodilution

In Vitro Hypothermia Enhances Platelet GPIIb-IIIa Activation and P-Selectin Expression

FIBRINOGEN-HEPATITIS RISK

THROMBIN–FIBRINOGEN INTERACTION

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