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Articles

Deranged Balance of Hemostasis and Fibrinolysis in Disseminated Intravascular Coagulation: Assessment and Relevance in Different Clinical Settings

Ecaterina Scarlatescu, M.D., M.Sc., Ph.D., Toshiaki Iba, M.D., Ph.D., Cheryl L. Maier, M.D., Ph.D., Hunter Moore, M.D., Maha Othman, M.D., M.Sc., Ph.D., Jean Marie Connors, M.D., Jerrold H. Levy, M.D.

Anesthesiology. September 2024: 141(3):570–583

https://doi.org/10.1097/ALN.0000000000005023

Published: September 2024

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Articles

Fibrinolysis as a Causative Mechanism for Bleeding Complications on Extracorporeal Membrane Oxygenation: A Pilot Observational Prospective Study

Julie Helms, M.D., Ph.D., Anaïs Curtiaud, M.D., François Severac, M.D., Marine Tschirhart, Pharm.D., Hamid Merdji, M.D., Ph.D., Matthieu Bourdin, B.E., Geneviève Contant, Pharm.D., François Depasse, Pharm.D., Ramy Abou Rjeily, Pharm.D., Laurent Sattler, Pharm.D., Ferhat Meziani, M.D., Ph.D., Eduardo Angles-Cano, M.D., S.C.D.

Anesthesiology. July 2024: 141(1):75–86

https://doi.org/10.1097/ALN.0000000000004980

Published: July 2024

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Articles

Coagulopathy Underlying Rotational Thromboelastometry Derangements in Trauma Patients: A Prospective Observational Multicenter Study

Romein W. G. Dujardin, M.D., Derek J. B. Kleinveld, Ph.D., Christine Gaarder, Ph.D., Karim Brohi, M.D., Ross A. Davenport, Ph.D., Nicola Curry, M.D., Simon Stanworth, Ph.D., Pär I. Johansson, Ph.D., Jakob Stensballe, Ph.D., Marc Maegele, Ph.D., Nicole P. Juffermans, Ph.D.

Anesthesiology. August 2022: 137(2):232–242

https://doi.org/10.1097/ALN.0000000000004268

Published: August 2022

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Articles

Suppression of Fibrinolysis and Hypercoagulability, Severity of Hypoxemia, and Mortality in COVID-19 Patients: A Retrospective Cohort Study

Kristin M. Corey, M.D., Lyra B. Olson, Ph.D., Ibtehaj A. Naqvi, M.D., Ph.D., Sarah A. Morrison, Ph.D., Connor Davis, B.S., Shahid M. Nimjee, M.D., Ph.D., Loretta G. Que, M.D., Robin E. Bachelder, Ph.D., Bryan D. Kraft, M.D., Lingye Chen, M.D., Smita K. Nair, Ph.D., Jerrold H. Levy, M.D., Bruce A. Sullenger, Ph.D.

Anesthesiology. July 2022: 137(1):67–78

https://doi.org/10.1097/ALN.0000000000004239

Published: July 2022

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Articles

Fibrinolysis and Trauma Outcomes

Paul S. Myles, M.B., B.S., M.P.H., M.D., D.Sc., F.C.A.I., F.A.N.Z.C.A., F.R.C.A., F.A.H.M.S., Robert Medcalf, B.Sc.(Hons), Ph.D.

Anesthesiology. January 2022: 136(1):7–9

https://doi.org/10.1097/ALN.0000000000004020

Published: January 2022

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Articles

Fibrinolysis Transitions: Adverse Outcomes in Trauma

Jonathan P. Wanderer, James P. Rathmell

Anesthesiology. January 2022: 136(1):A17

https://doi.org/10.1097/ALN.0000000000004100

Published: January 2022

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Articles

Temporal Transitions in Fibrinolysis after Trauma: Adverse Outcome Is Principally Related to Late Hypofibrinolysis

Andrea Rossetto, M.D., Paul Vulliamy, Ph.D., Kim May Lee, Ph.D., Karim Brohi, M.D., Ross Davenport, Ph.D.

Anesthesiology. January 2022: 136(1):148–161

https://doi.org/10.1097/ALN.0000000000004036

Published: January 2022

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Articles

COVID-19–associated Coagulopathy: Less Fibrinolysis Can Be More Harmful!

Klaus Görlinger, M.D., Jerrold H. Levy, M.D., F.A.H.A., F.C.C.M.

Anesthesiology. March 2021: 134(3):366–369

https://doi.org/10.1097/ALN.0000000000003688

Published: March 2021

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Articles

Greater Fibrinolysis Resistance but No Greater Platelet Aggregation in Critically Ill COVID-19 Patients

Christoph Heinz, M.D., Wolfgang Miesbach, M.D., Eva Herrmann, Ph.D., Michael Sonntagbauer, M.D., Florian J. Raimann, M.D., Kai Zacharowski, M.D., Ph.D., Christian F. Weber, M.D., Elisabeth H. Adam, M.D.

Anesthesiology. March 2021: 134(3):457–467

https://doi.org/10.1097/ALN.0000000000003685

Published: March 2021

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Articles

Antifibrinolytic Therapy and Perioperative Considerations

Jerrold H. Levy, M.D., F.A.H.A., F.C.C.M., Andreas Koster, M.D., Quintin J. Quinones, M.D., Ph.D., Truman J. Milling, M.D., Nigel S. Key, M.B., Ch.B., F.R.C.P.

Anesthesiology. March 2018: 128(3):657–670

https://doi.org/10.1097/ALN.0000000000001997

Published: March 2018

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Articles

Fulminant Hyperfibrinolysis Diagnosed by Rotational Thromboelastometry

John S. McNeil, M.D., Amanda M. Kleiman, M.D.

Anesthesiology. November 2017: 127(5):892

https://doi.org/10.1097/ALN.0000000000001742

Published: November 2017

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Articles

Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy

Ross A. Davenport, Ph.D., Maria Guerreiro, M.D., Daniel Frith, Ph.D., Claire Rourke, B.Sc., Sean Platton, B.Sc., Mitchell Cohen, M.D., Rupert Pearse, Ph.D., Chris Thiemermann, Ph.D., Karim Brohi, M.D.

Anesthesiology. January 2017: 126(1):115–127

https://doi.org/10.1097/ALN.0000000000001428

Published: January 2017

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Articles

Anesthesia Literature Review

Timothy J. Brennan, Ph.D., M.D.

Anesthesiology. December 2011: 115(6):1303–1307

https://doi.org/10.1097/ALN.0b013e318238ebe5

Published: December 2011

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Articles

Pathophysiology and Treatment of Coagulopathy in Massive Hemorrhage and Hemodilution

Daniel Bolliger, M.D., Klaus Görlinger, M.D., Kenichi A. Tanaka, M.D., M.Sc., David S. Warner, M.D.

Anesthesiology. November 2010: 113(5):1205–1219

https://doi.org/10.1097/ALN.0b013e3181f22b5a

Published: November 2010

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Articles

CU-2010—A Novel Small Molecule Protease Inhibitor with Antifibrinolytic and Anticoagulant Properties

Wulf Dietrich, M.D., Ph.D., Silke Nicklisch, M.Sc., Andreas Koster, M.D., Ph.D., Michael Spannagl, M.D., Ph.D., Helmut Giersiefen, Ph.D., Andreas van de Locht, Ph.D.

Anesthesiology. January 2009: 110(1):123–130

https://doi.org/10.1097/ALN.0b013e318191408c

Published: January 2009

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Articles

Mechanical Ventilation with Lower Tidal Volumes and Positive End-expiratory Pressure Prevents Alveolar Coagulation in Patients without Lung Injury

Goda Choi, M.D., Esther K. Wolthuis, M.D., Paul Bresser, M.D., Ph.D., Marcel Levi, M.D., Ph.D., Tom van der Poll, M.D., Ph.D., Misa Dzoljic, M.D., Ph.D., Margreeth B. Vroom, M.D., Ph.D., Marcus J. Schultz, M.D., Ph.D.

Anesthesiology. October 2006: 105(4):689–695

https://doi.org/10.1097/00000542-200610000-00013

Published: October 2006

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Articles

Activation of Coagulation and Fibrinolysis during Coronary Surgery: On-pump versusOff-pump Techniques

Valter Casati, M.D., Chiara Gerli, M.D., Annalisa Franco, M.D., Patrizia Della Valle, B.S., Stefano Benussi, M.D., Ottavio Alfieri, M.D., Giorgio Torri, M.D., Armando D’Angelo, M.D.

Anesthesiology. November 2001: 95(5):1103–1109

https://doi.org/10.1097/00000542-200111000-00013

Published: November 2001

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Articles

Room D, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Myocardial Ischemia Initiates Intracoronary Fibrinolysis : A-614

B. Osterlund, MD, S. Haggmark, G. Johansson, H. Seeman-Lodding, MD, B. Biber, Prof

Anesthesiology. September 2000: 93(3A):A–614

https://doi.org/10.1097/00000542-200009001-00614

Published: September 2000

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Articles

The Effect of Prophylactic ε-Aminocaproic Acid on Bleeding, Transfusions, Platelet Function, and Fibrinolysis during Coronary Artery Bypass Grafting

Christopher A. Troianos, MD, Richard W. Sypula, MD, Donna M. Lucas, MD, Frank D'Amico, PhD, Thomas B. Mathie, BS, Manish Desai, BS, Roberta T. Pasqual, PhD, Ronald V. Pellegrini, MD, Mark L. Newfeld, MD

Anesthesiology. August 1999: 91(2):430–435

https://doi.org/10.1097/00000542-199908000-00017

Published: August 1999

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Articles

The Effects of Different Anesthetic Regimens on Fibrinolysis and the Development of Postoperative Arterial Thrombosis

Brian A. Rosenfeld, M.D., Charles Beattie, Ph.D., M.D., Rose Christopherson, M.D., Ph.D., Edward J. Norris, M.D., Steven M. Frank, M.D., Michael J. Breslow, M.D., Peter Rock, M.D., Stephen D. Parker, M.D., Sidney O. Gottlieb, M.D., Bruce A. Perler, M.D., G Melville Williams, M.D., Alex Seidler, Ph.D., William Bell, M.D., The Perioperative Ischemia Randomized Anesthesia Trial Study Group

Anesthesiology. September 1993: 79(3):435–443

https://doi.org/10.1097/00000542-199309000-00005

Published: September 1993

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NARROW

Deranged Balance of Hemostasis and Fibrinolysis in Disseminated Intravascular Coagulation: Assessment and Relevance in Different Clinical Settings

Fibrinolysis as a Causative Mechanism for Bleeding Complications on Extracorporeal Membrane Oxygenation: A Pilot Observational Prospective Study

Coagulopathy Underlying Rotational Thromboelastometry Derangements in Trauma Patients: A Prospective Observational Multicenter Study

Suppression of Fibrinolysis and Hypercoagulability, Severity of Hypoxemia, and Mortality in COVID-19 Patients: A Retrospective Cohort Study

Fibrinolysis and Trauma Outcomes

Fibrinolysis Transitions: Adverse Outcomes in Trauma

Temporal Transitions in Fibrinolysis after Trauma: Adverse Outcome Is Principally Related to Late Hypofibrinolysis

COVID-19–associated Coagulopathy: Less Fibrinolysis Can Be More Harmful!

Greater Fibrinolysis Resistance but No Greater Platelet Aggregation in Critically Ill COVID-19 Patients

Antifibrinolytic Therapy and Perioperative Considerations

Fulminant Hyperfibrinolysis Diagnosed by Rotational Thromboelastometry

Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy

Anesthesia Literature Review

Pathophysiology and Treatment of Coagulopathy in Massive Hemorrhage and Hemodilution

CU-2010—A Novel Small Molecule Protease Inhibitor with Antifibrinolytic and Anticoagulant Properties

Mechanical Ventilation with Lower Tidal Volumes and Positive End-expiratory Pressure Prevents Alveolar Coagulation in Patients without Lung Injury

Activation of Coagulation and Fibrinolysis during Coronary Surgery: On-pump versusOff-pump Techniques

Room D, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Myocardial Ischemia Initiates Intracoronary Fibrinolysis : A-614

The Effect of Prophylactic ε-Aminocaproic Acid on Bleeding, Transfusions, Platelet Function, and Fibrinolysis during Coronary Artery Bypass Grafting

The Effects of Different Anesthetic Regimens on Fibrinolysis and the Development of Postoperative Arterial Thrombosis

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