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Articles

Combination of a δ-opioid Receptor Agonist and Loperamide Produces Peripherally-mediated Analgesic Synergy in Mice

Daniel J. Bruce, B.A., Cristina D. Peterson, Ph.D., Kelley F. Kitto, Eyup Akgün, Ph.D., Sophia Lazzaroni, B.S., Phillip S. Portoghese, Ph.D., Carolyn A. Fairbanks, Ph.D., George L. Wilcox, Ph.D.
Publication: Anesthesiology
Anesthesiology. September 2019: 131(3):649–663
https://doi.org/10.1097/ALN.0000000000002840
Published: September 2019
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Overexpression of µ-Opioid Receptors in Peripheral Afferents, but Not in Combination with Enkephalin, Decreases Neuropathic Pain Behavior and Enhances Opioid Analgesia in Mouse

Amanda H. Klein, Ph.D., M.S., Husam K. Mohammad, Ph.D., R.Ph., Rabiah Ali, M.D., Brad Peper, D.M.D., Steven P. Wilson, Ph.D., Srinivasa N. Raja, M.D., Matthias Ringkamp, M.D., Ph.D., Sarah Sweitzer, Ph.D.
Publication: Anesthesiology
Anesthesiology. May 2018: 128(5):967–983
https://doi.org/10.1097/ALN.0000000000002063
Published: May 2018
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Tariquidar, a Selective P-glycoprotein Inhibitor, Does Not Potentiate Loperamide’s Opioid Brain Effects in Humans despite Full Inhibition of Lymphocyte P-glycoprotein

Daniel Kurnik, M.D., Gbenga G. Sofowora, M.D., John P. Donahue, Ph.D., Usha B. Nair, Ph.D., Grant R. Wilkinson, Ph.D., Alastair J. J. Wood, M.D., Mordechai Muszkat, M.D.
Publication: Anesthesiology
Anesthesiology. December 2008: 109(6):1092–1099
https://doi.org/10.1097/ALN.0b013e31818d8f28
Published: December 2008
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Enhanced Peripheral Analgesia Using Virally Mediated Gene Transfer of the μ-Opioid Receptor in Mice

Guohua Zhang, M.D., Ph.D., Husam Mohammad, B.S., Brad D. Peper, B.A., Srinivasa Raja, M.D., Steven P. Wilson, Ph.D., Sarah M. Sweitzer, Ph.D.
Publication: Anesthesiology
Anesthesiology. February 2008: 108(2):305–313
https://doi.org/10.1097/01.anes.0000299836.61785.79
Published: February 2008
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Interaction of Morphine, Fentanyl, Sufentanil, Alfentanil, and Loperamide with the Efflux Drug Transporter P-glycoprotein

Christoph Wandel, M.D., Richard Kim, M.D., Margaret Wood, M.B.Ch.B., F.R.C.A., Alastair Wood, M.B.Ch.B., F.R.C.P.
Publication: Anesthesiology
Anesthesiology. April 2002: 96(4):913–920
https://doi.org/10.1097/00000542-200204000-00019
Published: April 2002
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Articles

Characterization of the Antihyperalgesic Action of a Novel Peripheral Mu-opioid Receptor Agonist-Loperamide

Natsuko Nozaki-Taguchi, MD, Tony L. Yaksh, PhD
Publication: Anesthesiology
Anesthesiology. January 1999: 90(1):225–234
https://doi.org/10.1097/00000542-199901000-00029
Published: January 1999
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