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TREK-1 and TREK-2 Knockout Mice Are Not Resistant to Halothane or Isoflurane

Kira A. Spencer, Ph.D., Christian B. Woods, B.S., Hailey M. Worstman, B.A., Simon C. Johnson, Ph.D., Jan-Marino Ramirez, Ph.D., Philip G. Morgan, M.D., Margaret M. Sedensky, M.D.

Anesthesiology. July 2023: 139(1):63–76

https://doi.org/10.1097/ALN.0000000000004577

Published: July 2023

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Articles

Guanylyl Cyclase A in Both Renal Proximal Tubular and Vascular Endothelial Cells Protects the Kidney against Acute Injury in Rodent Experimental Endotoxemia Models

Hiroaki Kitamura, M.D., Daisuke Nakano, Ph.D., Yoshiharu Sawanobori, M.D., Takehiko Asaga, M.D., Ph.D., Hideki Yokoi, M.D., Ph.D., Motoko Yanagita, M.D., Ph.D., Masashi Mukoyama, M.D., Ph.D., Takeshi Tokudome, M.D., Ph.D., Kenji Kangawa, Ph.D., Gotaro Shirakami, M.D., Ph.D., Akira Nishiyama, M.D., Ph.D.

Anesthesiology. August 2018: 129(2):296–310

https://doi.org/10.1097/ALN.0000000000002214

Published: August 2018

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Articles

Hypnotic Hypersensitivity to Volatile Anesthetics and Dexmedetomidine in Dopamine β-Hydroxylase Knockout Mice

Frances Y. Hu, B.A., George M. Hanna, M.D., Wei Han, B.S., Feras Mardini, B.S., Steven A. Thomas, M.D., Ph.D., Abraham J. Wyner, Ph.D., Max B. Kelz, M.D. Ph.D.

Anesthesiology. November 2012: 117(5):1006–1017

https://doi.org/10.1097/ALN.0b013e3182700ab9

Published: November 2012

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Articles

Isozyme-specific Effects of Protein Kinase C in Pain Modulation

Chengshui Zhao, M.D., Ph.D., Michael Leitges, Ph.D., Robert W. Gereau, Ph.D.

Anesthesiology. December 2011: 115(6):1261–1270

https://doi.org/10.1097/ALN.0b013e3182390788

Published: December 2011

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Articles

TASK Channel Deletion Reduces Sensitivity to Local Anesthetic-induced Seizures

Guizhi Du, M.D., Xiangdong Chen, M.D., Ph.D., Marko S. Todorovic, B.S., Shaofang Shu, B.S., Jaideep Kapur, M.D., Douglas A. Bayliss, Ph.D.

Anesthesiology. November 2011: 115(5):1003–1011

https://doi.org/10.1097/ALN.0b013e3182343660

Published: November 2011

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Articles

ARA290, a Peptide Derived from the Tertiary Structure of Erythropoietin, Produces Long-term Relief of Neuropathic Pain: An Experimental Study in Rats and β-Common Receptor Knockout Mice

Maarten Swartjes, B.Sc., Aurora Morariu, M.D., Ph.D., Marieke Niesters, M.D., M.Sc., Michael Brines, M.D., Ph.D., Anthony Cerami, Ph.D., Leon Aarts, M.D., Ph.D., Albert Dahan, M.D., Ph.D.

Anesthesiology. November 2011: 115(5):1084–1092

https://doi.org/10.1097/ALN.0b013e31822fcefd

Published: November 2011

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Articles

A Peripheral Adrenoceptor-mediated Sympathetic Mechanism Can Transform Stress-induced Analgesia into Hyperalgesia

John E. Donello, Ph.D., Yun Guan, M.D., Ph.D., Mingting Tian, M.S., Cynthia V. Cheevers, B.S., Miguel Alcantara, B.S., Sara Cabrera, M.S., Srinivasa N. Raja, M.D., Daniel W. Gil, Ph.D.

Anesthesiology. June 2011: 114(6):1403–1416

https://doi.org/10.1097/ALN.0b013e31821c3878

Published: June 2011

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Articles

Discrete Change in Volatile Anesthetic Sensitivity in Mice with Inactivated Tandem Pore Potassium Ion Channel TRESK

Yun Jeong Chae, M.D., Ph.D., Jianan Zhang, M.S., Paul Au, B.S., Marta Sabbadini, Ph.D., Guo-Xi Xie, M.D., Ph.D., C. Spencer Yost, M.D.

Anesthesiology. December 2010: 113(6):1326–1337

https://doi.org/10.1097/ALN.0b013e3181f90ca5

Published: December 2010

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Articles

2009 in Review: Advancing Medicine in Anesthesiology

Alain Borgeat, M.D., Timothy J. Brennan, Ph.D., M.D., James C. Eisenach, M.D., Hugh C. Hemmings, M.D., Ph.D., Shiroh Isono, M.D., Judy R. Kersten, M.D., Eberhard Kochs, M.D., Ph.D., Bruno Riou, M.D., Ph.D., David S. Warner, M.D., Ph.D.

Anesthesiology. December 2009: 111(6):1192–1196

https://doi.org/10.1097/ALN.0b013e3181c1879b

Published: December 2009

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Articles

α-1-Adrenergic Receptor Agonist Activity of Clinical α-Adrenergic Receptor Agonists Interferes with α-2-Mediated Analgesia

Daniel W. Gil, Ph.D., Cynthia V. Cheevers, B.S., Karen M. Kedzie, Ph.D., Cynthia A. Manlapaz, B.S., M.B.A., Sandhya Rao, M.S., Elaine Tang, B.S., John E. Donello, Ph.D.

Anesthesiology. February 2009: 110(2):401–407

https://doi.org/10.1097/ALN.0b013e3181943226

Published: February 2009

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Articles

Differential Effects of α 2 -adrenoceptors in the Modulation of the Thermoregulatory Response in Mice Induced by Meperidine

Jan Höcker, M.D., Andrea Paris, M.D., Jens Scholz, M.D., Peter H. Tonner, M.D., Martin Nielsen, M.S., Berthold Bein, M.D., D.E.A.A.

Anesthesiology. July 2008: 109(1):95–100

https://doi.org/10.1097/ALN.0b013e31817c02fc

Published: July 2008

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Articles

Sensory Processing in the Deep Spinal Dorsal Horn of Neurokinin-1 Receptor Knockout Mice

Han-Rong Weng, M.D., Ph.D., Heikki Mansikka, M.D., Ronald Winchurch, Ph.D., Srinivasa N. Raja, M.D., Patrick M. Dougherty, Ph.D.

Anesthesiology. June 2001: 94(6):1105–1112

https://doi.org/10.1097/00000542-200106000-00027

Published: June 2001

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Articles

Anesthetic Potency and Influence of Morphine and Sevoflurane on Respiration in μ-Opioid Receptor Knockout Mice

Albert Dahan, M.D., Ph.D., Elise Sarton, M.D., Ph.D., Luc Teppema, Ph.D., Cees Olievier, Diederik Nieuwenhuijs, M.D., Hans W. D. Matthes, Ph.D., Brigitte L. Kieffer, Ph.D.

Anesthesiology. May 2001: 94(5):824–832

https://doi.org/10.1097/00000542-200105000-00021

Published: May 2001

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Articles

Opiate-induced Analgesia Is Increased and Prolonged in Mice Lacking P-glycoprotein

Susan J. Thompson, M.D., Ph.D., Kari Koszdin, D.V.M., Christopher M. Bernards, M.D.

Anesthesiology. May 2000: 92(5):1392–1399

https://doi.org/10.1097/00000542-200005000-00030

Published: May 2000

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Articles

Neurokinin-1 Receptors Are Involved in Behavioral Responses to High-intensity Heat Stimuli and Capsaicin-induced Hyperalgesia in Mice

Heikki Mansikka, MD, PhD, Masako Shiotani, MD, Richard Winchurch, PhD, Srinivasa N. Raja, MD

Anesthesiology. June 1999: 90(6):1643–1649.

https://doi.org/10.1097/00000542-199906000-00021

Published: June 1999

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Articles

Isoflurane-induced Cerebral Hyperemia in Neuronal Nitric Oxide Synthase Gene Deficient Mice

Hirotsugu Okamoto, MD, PhD, Wei Meng, MD, Jinya Ma, MD, Cenk Ayata, MD, Richard J. Roman, PhD, Zeljko J. Bosnjak, PhD, John P. Kampine, MD, PhD, Paul L. Huang, MD, PhD, Michael A. Moskowitz, MD, Antal G. Hudetz, BMD, PhD

Anesthesiology. April 1997: 86(4):875–884

https://doi.org/10.1097/00000542-199704000-00018

Published: April 1997

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Articles

Effects of Targeted Neuronal Nitric Oxide Synthase Gene Disruption and Nitro sup G -L-Arginine Methylester on the Threshold for Isoflurane Anesthesia

Fumito Ichinose, MD, Paul L. Huang, MD, Warren M. Zapol, MD

Anesthesiology. July 1995: 83(1):101–108.

https://doi.org/10.1097/00000542-199507000-00013

Published: July 1995

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NARROW

TREK-1 and TREK-2 Knockout Mice Are Not Resistant to Halothane or Isoflurane

Guanylyl Cyclase A in Both Renal Proximal Tubular and Vascular Endothelial Cells Protects the Kidney against Acute Injury in Rodent Experimental Endotoxemia Models

Hypnotic Hypersensitivity to Volatile Anesthetics and Dexmedetomidine in Dopamine β-Hydroxylase Knockout Mice

Isozyme-specific Effects of Protein Kinase C in Pain Modulation

TASK Channel Deletion Reduces Sensitivity to Local Anesthetic-induced Seizures

ARA290, a Peptide Derived from the Tertiary Structure of Erythropoietin, Produces Long-term Relief of Neuropathic Pain: An Experimental Study in Rats and β-Common Receptor Knockout Mice

A Peripheral Adrenoceptor-mediated Sympathetic Mechanism Can Transform Stress-induced Analgesia into Hyperalgesia

Discrete Change in Volatile Anesthetic Sensitivity in Mice with Inactivated Tandem Pore Potassium Ion Channel TRESK

2009 in Review: Advancing Medicine in Anesthesiology

α-1-Adrenergic Receptor Agonist Activity of Clinical α-Adrenergic Receptor Agonists Interferes with α-2-Mediated Analgesia

Differential Effects of α 2 -adrenoceptors in the Modulation of the Thermoregulatory Response in Mice Induced by Meperidine

Sensory Processing in the Deep Spinal Dorsal Horn of Neurokinin-1 Receptor Knockout Mice

Anesthetic Potency and Influence of Morphine and Sevoflurane on Respiration in μ-Opioid Receptor Knockout Mice

Opiate-induced Analgesia Is Increased and Prolonged in Mice Lacking P-glycoprotein

Neurokinin-1 Receptors Are Involved in Behavioral Responses to High-intensity Heat Stimuli and Capsaicin-induced Hyperalgesia in Mice

Isoflurane-induced Cerebral Hyperemia in Neuronal Nitric Oxide Synthase Gene Deficient Mice

Effects of Targeted Neuronal Nitric Oxide Synthase Gene Disruption and Nitro sup G -L-Arginine Methylester on the Threshold for Isoflurane Anesthesia

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