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Anesthetics, intravenous: methohexital

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Articles
Publication: Anesthesiology
Anesthesiology. August 2019: 131(2):287–304
Published: August 2019
... at anesthetic doses and seizures in dogs at 10-fold higher toxicologic doses The mechanism of seizures in dogs, and their relationship to involuntary muscle movements in humans, is unknown What This Article Tells Us That Is New Toxicologic studies in dogs using supratherapeutic ABP-700 doses caused involuntary...
Articles
Articles
Publication: Anesthesiology
Anesthesiology. October 2015: 123(4):937–960
Published: October 2015
... states of patients receiving anesthesia care. Here in part I, we review the biophysics of the electroencephalogram and the neurophysiology of the electroencephalogram signatures of three intravenous anesthetics: propofol, dexmedetomidine, and ketamine, and four inhaled anesthetics: sevoflurane...
Articles
Publication: Anesthesiology
Anesthesiology. August 2015: 123(2):368–376
Published: August 2015
.... Anesth Analg 1977 ; 56 : 717 – 9 7. Lamalle D : Cardiovascular effects of various anesthetics in man. Four short-acting intravenous anesthetics: Althesin, etomidate, methohexital and propanidid. Acta Anaesthesiol Belg 1976 ; 27 ( suppl ): 208 – 24 8. Colvin MP , Savege...
Articles
Publication: Anesthesiology
Anesthesiology. March 2015: 122(3):495–520
Published: March 2015
... is not available, inhalation anesthetics may be administered from an anesthesia machine inside zone III via an elongated circuit through a wave guide. Finally, both the consultants and ASA members agree that, if total intravenous anesthesia is used, it should be administered by using: (1) MRI safe/conditional...
Articles
Publication: Anesthesiology
Anesthesiology. August 2014: 121(2):290–301
Published: August 2014
...-barbiturate intravenous induction agent. Lancet 1975 ; 1 : 955 – 6 4. Lamalle D : Cardiovascular effects of various anesthetics in man. Four short-acting intravenous anesthetics: Althesin, etomidate, methohexital and propanidid. Acta Anaesthesiol Belg 1976 ; 27 ( suppl ): 208 – 24...
Articles
Publication: Anesthesiology
Anesthesiology. March 2014: 120(3):760–772
Published: March 2014
...: The dorsal microcirculatory chamber. Br J Anaesth 2000 ; 85 : 901 – 3 156. Brookes ZL , Brown NJ , Reilly CS : Response of the rat cremaster microcirculation to hemorrhage in vivo : Differential effects of intravenous anesthetic agents. Shock 2002 ; 18 : 542 – 8 157...
Articles
Publication: Anesthesiology
Anesthesiology. October 2013: 119(4):848–860
Published: October 2013
...) and a USB-6009 14-bit data-acquisition board (National Instruments, Austin, TX). The sampling rate was 512 Hz. A line filter with cutoff frequencies of 0.3 and 50 Hz was used. Rats were anesthetized in an induction chamber with 2–3% isoflurane in oxygen before the placement of a 24-gauge intravenous...
Articles
Publication: Anesthesiology
Anesthesiology. September 2013: 119(3):663–674
Published: September 2013
... intravenous injection on 2 separate study days. On one occasion, ventilation at a clamped increased carbon dioxide concentration was measured and on another the pain tolerance to electrical stimulation. In both sessions, arterial plasma samples were obtained. The data were analyzed with a population...
Articles
Publication: Anesthesiology
Anesthesiology. February 2012: 116(2):286–295
Published: February 2012
..., multicenter randomized study. Gastrointest Endosc 2011; 73:765–72 34. Zhang XS RR, Huang JW: Closed-loop system for total intravenous anesthesia by simultaneously administering two anesthetic drugs. IEEE Eng Med Biol Mag 1998; 6:3052–5 35. Vakkuri A, Yli-Hankala A, Sandin R, Mustola S, Hymork S...
Articles
Publication: Anesthesiology
Anesthesiology. March 2011: 114(3):695–707
Published: March 2011
... in its unusually favorable safety profile. 5 Table 1.   Acute Toxicity Ratios of Intravenous Anesthetic Induction Drugs Etomidate was introduced into clinical practice in 1972, and initial reports of its use in humans emerged in the clinical literature soon afterward. 6,7 Academic...
Articles
Publication: Anesthesiology
Anesthesiology. December 2008: 109(6):1132–1136
Published: December 2008
... a widely accepted approach for elective surgery. As the volume and complexity of ambulatory surgery procedures increased, it became apparent that the traditional intravenous ( e.g.  , barbiturates [thiopental, methohexital]) and volatile (halothane, enflurane, isoflurane) anesthetics were associated...
Articles
Publication: Anesthesiology
Anesthesiology. January 2010: 112(1):86–101
Published: January 2010
... and isoflurane groups, reported no differences in infarction volume or neurologic outcome 8 days after temporary focal ischemia. Therefore, it is possible that, as has been observed for other anesthetics, 53–55 barbiturates might only improve short-term outcomes, with neurologic benefits dissipating over time...
Articles
Publication: Anesthesiology
Anesthesiology. November 2007: 107(5):857–858
Published: November 2007
... standards of care. For example, a typical clinical recommendation for adult methohexital administration is 1–1.5 mg/kg intravenous for induction, and 20–40 mg intravenous every 4–7 min for maintenance. 2 However, in our case, the patient was completely awake, responsive to complex yes/no questions with toe...
Articles
Publication: Anesthesiology
Anesthesiology. December 2008: 109(6):1113–1131
Published: December 2008
... a pressure decrease caused by SNP (2–3 μg/kg intravenous) yielding an average baroreflex gain. Average baroreflex gain assessed by this conventional method was compared with baroreflex gain assessed during spontaneous arterial pressure fluctuations. Resting MSA was 28 bursts/100 heartbeats at a diastolic...
Articles
Publication: Anesthesiology
Anesthesiology. March 2009: 110(3):459–479
Published: March 2009
... anesthetics can be administered from an anesthesia machine inside zone III via   an elongated circuit through a wave guide. -If total intravenous anesthesia is used, it should be administered by using (1) MRI-safe/conditional pumps in zone IV, (2) traditional ( i.e.  , MRI unsafe) pumps in zone III...
Articles
Publication: Anesthesiology
Anesthesiology. November 2007: 107(5):857
Published: November 2007
... able to communicate (many cannot because of psychiatric illness). Repeated ECT raises seizure thresholds, reducing duration and effectiveness, often requiring changes from methohexital to induction agents less inhibitory, including etomidate to ketamine. Meticulous vigilance to ensure effective amnesia...
Articles
Publication: Anesthesiology
Anesthesiology. September 2008: 109(3):543–564
Published: September 2008
... of intracarotid drugs. 32 FOR more than 50 yr, intracarotid anesthetic drugs have been used in diagnostic neuroradiology to locate brain functions. 1 In the 1980s, intracarotid drugs were extensively investigated for the treatment of malignant brain tumors. 2–6 However, the attempts at intracarotid...
Articles
Publication: Anesthesiology
Anesthesiology. April 2008: 108(4):756–758
Published: April 2008
.... Local anesthesia with little or no preoperative sedation is currently recommended as the anesthetic of choice for temporary carotid occlusion during carotid endarterectomy. Purported advantages include minimal circulatory and respiratory changes from the local anesthetic, and constant verbal contact can...
Articles
Publication: Anesthesiology
Anesthesiology. April 2007: 106(4):871–872
Published: April 2007
... for electroconvulsive therapy (ECT). 1 We now report a case of awareness during anesthesia just before the ECT electroshock, but with no post-ECT recall. We began again with preoxygenation, but unconsciousness was induced with intravenous etomidate (12 mg) instead of methohexital. Succinylcholine (80 mg) was again...