... of Intralipid, sevoflurane, and remifentanil during DCD heart resuscitation on the ESHP apparatus would accelerate recovery of left ventricular (LV) mechanical function and improve heart viability, thereby providing superior organ preservation over a clinically relevant duration of 6 h of ESHP, allowing...

... LV-CS. Right ventricular stroke work index was decreased with increased PEEP. Despite a minor increase in heart rate (HR) at PEEP levels of 15 cmH 2 O (71 bpm vs. 75 bpm, p<0.05), total mechanical power expenditure (PVA normalized to HR) decreased at higher PEEP. Conclusions Applying higher PEEP...

... of existing heart failure. Both pulmonary artery pressures and right ventricular afterload are increased by exposure to ambient PM, while increased arterial vasoconstriction elevates left ventricular afterload. When combined with PM-induced blunting of urinary sodium excretion, wildfire smoke markedly...

... indications or contraindications to FEIBA to reduce confounding, therefore we are unable to comment on these populations. This also limits the generalizability of findings for other institutions that may administer FEIBA in the context of cardiac surgery. Finally, heart transplants and VAD procedures...

..., no gray zone) separated for invasive and noninvasive arterial waveform analysis. AUC, area under the receiver operating characteristics curve. Fig. 5. Receiver operating characteristics curves for stroke volume (SV), heart rate (HR), and mean arterial pressure (MAP) predicting a decrease below...

...) to support editing the manuscript, creating tabular representations, and facilitating brainstorming. Supported by a Swiss National Science Foundation (Bern, Switzerland) grant (project grant 310030_197823) to Dr. Schaer and National Institutes of Health (National Heart, Lung, and Blood Institute...

.... Lancet 2015 ; 386 : 1243 – 53 8. Myles PS , Dieleman JM , Forbes A , Heritier S , Smith JA : Dexamethasone for cardiac surgery trial (DECS-II): Rationale and a novel, practice preference-randomized consent design. Am Heart J 2018 ; 204 : 52 – 7 9...

... : Propofol inhibits SIRT2 deacetylase through a conformation-specific, allosteric site. J Biol Chem 2015 ; 290 : 8559 – 68 22. Barajas MB , Brunner SD , Wang A , Griffiths KK , Levy RJ : Propofol toxicity in the developing mouse heart mitochondria. Pediatr Res 2022...

... to ventricular assist device and transplant persist after consideration for preferences for care: A report from the REVIVAL study. Circ Heart Fail 2023 ; 16 : e009745 49. Matthew Brennan J , Leon MB , Sheridan P : Racial differences in the use of aortic valve replacement...

..., it may have reduced the risk of harm from fluid administration in patients who are not fluid-responsive. Table 1. Major Randomized Clinical Trials Dynamic measurement of preload responsiveness (using heart-lung interactions such stroke volume variation, pulse pressure variation, or response...

... such as durable left ventricular assist device implantation or heart transplantation. Fig. 1. Peripheral venoarterial extracorporeal membrane oxygenation (ECMO). Femoral venous and arterial cannulation is shown. Venous drainage is pumped through an oxygenator and returned to the arterial circulation...

... pressures after abdominal wall closure may compromise cardiovascular function and renal perfusion, therefore postoperative intensive care unit management should be mandatory. Fig. 1. Complete Pentalogy of Cantrell with heart ( A ), diaphragm ( B ), liver ( C ), spleen ( D ), and stomach and small...

... arrhythmias until the onset of ventricular fibrillation. 37 Notably, two sequential clusters of increased coherence at 65 to 115 Hz and at 25 to 55 Hz coincided with distinct changes in heart rate, suggesting interactions between the brain and the heart during the dying process. 37 In a rat model...

... with veno-venous extracorporeal membrane oxygenation. Ann Intensive Care 2021 ; 11 : 101 10. Bachmann KF , Zwicker L , Nettelbeck K : Assessment of right heart function during extracorporeal therapy by modified thermodilution in a porcine model. A nesthesiology 2020...

..., ventricular assist devices, heart transplantation, and mini-invasive and robotic cardiac surgery. Personal/clinical exclusion criteria were preoperative delirium, psychiatric disorder, non–French-speaking patients, preoperative renal replacement therapy, chronic alcoholism, preoperative liver dysfunction...

... A , Blennow K , Zetterberg H , Ricksten SE : Open-heart surgery increases cerebrospinal fluid levels of Alzheimer-associated amyloid beta. Acta Anaesthesiol Scand 2013 ; 57 : 82 – 8 13. Tang JX , Baranov D , Hammond M , Shaw LM , Eckenhoff MF , Eckenhoff...

... to the heart and left ventricular ejection from the heart disproportionately affected both right ventricular and left ventricular function. The direct clinical implications of these results form the rationale for use of continuous positive airway pressure as a primary treatment of acute cardiogenic pulmonary...

... performed at a Philips Ingenia 3 tesla system with a 20-channel head–neck coil. A first phase-contrast magnetic resonance imaging plane was placed at the C2–C3 level of the neck, with the following parameters: retrospective gating using peripheral pulse recording, heart phases = 32, acquired voxel size = 1...

... , Lutchmedial S , Brunt KR , Simpson JA : Hemodynamic assessment of diastolic function for experimental models. Am J Physiol Heart Circ Physiol 2020 ; 318 : H1139 – 58 20. Chantler PD , Lakatta EG , Najjar SS : Arterial-ventricular coupling: Mechanistic insights...

... atrial and ventricular septal defects. Complex cyanotic heart defects like Tetralogy of Fallot were managed with palliative Blalock or Potts systemic-pulmonary shunts. I graduated from the University of Michigan Medical School (Ann Arbor, Michigan) in 1963 ( fig. 1 ). In 1965, I was a resident...