Monoclonal antibodies are proteins made by cloning a single B cell (hence “mono clonal”) into cultures that synthesize the antibody in sufficient quantities for research and, eventually, formulation into powerful medicine…. Last year, noted Harvard biologist William Haseltine predicted that monoclonal antibodies would be the first therapy specifically developed for SARS-CoV-2. He was right.

Transcatheter aortic valve replacement (TAVI) has become the standard of care for patients with severe symptomatic aortic stenosis. Since its introduction, the majority of TAVI procedures have been performed under general anesthesia. Initially developed as a less invasive alternative to surgical aortic valve replacement for high-risk or inoperable patients, its use has grown due to innovations in device design, smaller delivery systems, and increased procedural experience.

The annual J.P. Morgan Healthcare Conference in San Francisco is a January tradition at which the leading biotech and pharmaceutical companies announce their major news and discoveries. At this year’s virtual meeting, leaders from the pharmaceutical and biotech industries were focused on the COVID-19 pandemic.

Residency is an exciting but very stressful and confusing time for trainees. Residents must learn to balance clinical and academic commitments, career development and their personal lives, some without the support system of their families. An effective mentor’s support and guidance can profoundly alleviate some of the confusion and stress.