Which of the following is most likely indicated in the treatment of a patient with fibromyalgia syndrome (FMS)?

Not surprisingly, given that FMS may have multiple etiologies, there is little general agreement on which pharmacological agents are most effective in its treatment. One study that included 114 different rheumatology practices noted that the 214 patients treated for FMS received 74 different medications. Examples of more commonly used drugs include:

Although guaifenesin is commonly touted as a potential therapy on websites, there is no evidence that it is more effective than placebo in the treatment of patients with FMS.

Pregabalin, duloxetine and milnacipran have received approval from the U.S. Food and Drug Administration for treatment of patients with FMS.

Spinal cord stimulation is appropriate for treatment of regional pain syndromes, not the widespread pain of FMS.

Anesthesiology Continuing Education (ACE)...

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