The Committee on Problem-Based Learning Discussions invites submissions for the ANESTHESIOLOGY 2021 Problem-Based Learning Discussions (PBLDs) program planned for the host city of San Diego. This past October, 106 unique cases were scheduled and nearly all sessions sold out. There was lively debate and discussion in these first-ever virtual sessions held on Zoom. All PBLDs were scheduled over a one-hour period with a maximum of 11 participants and a moderator. For 2021, the committee will again continue the open-call process for PBLD case submissions. Submissions in each of the meeting tracks are being solicited, including ambulatory anesthesia, cardiac anesthesia, critical care medicine, fundamentals of anesthesia, geriatric anesthesia, neuroanesthesia, obstetric anesthesia, pain medicine, pediatric anesthesia, perioperative medicine, regional anesthesia, and professional issues. Submitted cases should only have one moderator, who must be at the faculty or attending level. For the past eight years, fellows have been allowed to submit cases together...

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