A 33-year-old woman was involved in an automobile collision with a deer and is quickly transported to your trauma center. According to a recent study, which of the following outcomes is MOST likely if you use a restrictive supplemental oxygen strategy to maintain her SpO2 at or above 94% versus using a liberal oxygen strategy to maintain her SpO2 above 98%?

After trauma, patients often receive supplemental oxygen in accordance with Advanced Trauma Life Support® (ATLS®) guidelines. However, this intervention may also result in hyperoxia. Although the additional oxygen may be beneficial when apnea develops during intubation, hyperoxia has been associated with the formation of detrimental reactive oxygen species that are also created during shock states. Additionally, there is conflicting evidence concerning the use of supplemental oxygen in the trauma patient.

As a result of this conflicting evidence, a recent pilot randomized clinical trial was...

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