UpToDate® and ASA Monitor are collaborating to present select content abstracts on “What's New in Anesthesiology.” UpToDate is an evidence-based, clinical support resource used worldwide by health care practitioners to make decisions at the point of care. For complete, current “What's New” content, or to become a subscriber for full content access, go to www.uptodate.com. “What's New” abstract information is free for all medical professionals.

Intraoperative neuromuscular block with rocuronium or vecuronium can be reversed with neostigmine or sugammadex. Side effects can occur with both drugs, but their relative safety has been unknown. In a retrospective review of adverse events in 90,000 surgical patients who received reversal, the incidence of a composite of clinically meaningful adverse events (ie, bronchospasm, anaphylaxis, bradycardia, cardiac arrest) was slightly greater with sugammadex than neostigmine (3.4 versus 3.0 percent) [1]. This difference was primarily related to an increase in bronchospasm and...

You do not currently have access to this content.