Fig. 4. Effects of propofol and ibuprofen on the pulmonary vasorelaxant response to arachidonic acid (AA) in endothelium-denuded rings (n = 6). Vasorelaxation expressed as percent reversal of phenylephrine (PE) contraction. Propofol (10−4m) and ibuprofen (10−5m) attenuated (* P < 0.05) AA-induced vasorelaxation to the same extent.