Table 5. Original versus Revised Pharmacokinetic Parameters for Propofol

* J. B. Dyck, Department of Anesthesia, Stanford University, Stanford, California, written communication, 1991.

† Revised pharmacokinetic parameters estimated from learning group (n = 19) using naïve pooled data approach.

‡ Based on prospective testing in the learning group (n = 19).

§ Compared with a simple three-compartment model without covariates.

CV = coefficient of variation of the revised pharmacokinetic parameters, as a measure of interindividual parameter variability estimated from monocular estimate method; LBM = lean body mass (kg); FBM = fat body mass (kg); wt = weight (kg); age (yr); LL = log likelihood; MDAWR = median absolute weighted residual; MDWR = median weighted residual.