Table 2. Gene Expression

Values are mean ± SD; n = 6.

* COX-2/L32 ratio greater in cardiopulmonary bypass (CPB) group versus  Sham;P = 0.013.

COX-2 and iNOS mRNA expression is quantitated relative to L32 mRNA expression, which serves as an internal loading control. Positive controls (n = 2) received intravenous lipopolysaccharide (LPS). Gene expression ratios were as follows: COX-2 in brain (0.98 and 1.04); COX-2 in liver (0 and 0.87); iNOS in brain (0 and 0); iNOS in liver (15.42 and 11.23).