Fig. 4. Effect of endothelial denudation (0.4% CHAPS) on isoflurane-mediated vasodilation in porcine coronary microvessels. Asterisks indicate a significant (P < 0.05) increase in arteriolar ID as compared with vessels before isoflurane exposure. Plus signs indicate a significant difference in isoflurane-mediated vasodilation between control and denuded arterioles at each isoflurane concentration. Vertical bars represent 1 ± SEM. Baseline values for ID in the control and denuded groups were 80 ± 6 and 76 ± 6 μm, respectively.