Fig. 8. Cumulative occurrence for (A ) consciousness (straight line), unconsciousness (dashed line) as described by the Observer's Assessment of Alertness/Sedation Scale (OAA/S; transition from level 3 to level 2) and (B ) as described by presence (straight line), loss (dashed line) of eyelash reflex as a function of the propofol effect-site concentration (Ce propofol). (C ) Cumulative occurrence for response (straight line), no response (dashed line) to noxious stimulus as a function of Ce propofol.