Table 1. Effects of PKC Activation on EAAT3 in the Presence or Absence of VAs

Oocytes either preincubated with PMA (100 nm for 10 min) or exposed to VA (0.70 mm for isoflurane, 0.59 mm for halothane, and 0.78 mm for sevoflurane) for 3 min showed greater responses than the control. Each set of data has been normalized by using the mean value of the control group from the same batch of oocytes (n = 3 or 4). Units are folds of controls, with controls being 1. Data are mean ± SEM (n = 12–18).

*P < 0.05 compared with control.

EAAT3 = excitatory amino acid transporter type 3; PKC = protein kinase C; PMA = phorbol 12-myrisate 13-acetate; VA = volatile anesthetic.