Fig. 2. Antinociceptive effect of the lamotrigine–morphine (MOR/LAM) combination during phase 1 (A ) and 2 (B ) of the formalin test. Rats were pretreated with combination into either the right or left (CL) paw, before formalin injection. Data are expressed as the percent antinociception. Data are the mean ± SEM for six animals. *Significantly different from the saline group (P < 0.05), as determined by analysis of variance followed by the Tukey test.