Fig. 1. The relation between the time course of the experiment and plasma propofol concentrations in the femoral artery or changes in cardiac output (CO) during constant infusion at 6 mg · kg−1· h−1in anesthetized swine. Circles show the CO at each time. Vertical bars represent 95% confidence intervals. Base 1 = baseline 1; High = high-CO state; Base 2 = baseline 2; Low = low-CO state.
