Fig. 1. Schematic illustration of the study design. In each subject, regional cerebral blood flow was assessed twice at each concentration level of sevoflurane (n = 8) or propofol (n = 8). Present data concern only the first flow scans at each level (gray arrows). Results of the auditory activation scans (white arrows) will be reported separately. The two cases of epileptiform discharges occurring during 2 MAC sevoflurane anesthesia 9are indicated by an asterisk.