Table 2. PK-PD fitting results of rocuronium and pancuronium at different flow rates
Results are given as mean values (SD). 200 μl/min (1), 200 μl/min (2) and 200 μl/min represent the first and second infusion and the mean values of the first and second infusion respectively.
† statistically significant (P < 0.05) differences between the first infusion at 200 μl/min and the infusion at 400 μl/min;
‡ statistically significant (P < 0.05) differences between the infusion at 400 μl/min and the second infusion at 200 μl/min;
* statistically significant (P < 0.05) differences between the first infusion at 200 μl/min and the second infusion at 200 μl/min;
§ statistically significant (P < 0.05) differences between the infusion at 400 μl/min and the mean of the two 200 μl/min infusions.
Ke0= rate of equilibration between plasma and biophase; PK–PD = pharmacokinetic-pharmacodynamic.