Fig. 4. Effect of nocodazole (5 μm, 30 min), vinblastine (10 μm, 30 min), or paclitaxel (8 μm, 30 min) on the amplitude of angiotensin II–induced Ca2+mobilization in cells from Wistar Kyoto rats (WKY;A ) and spontaneously hypertensive rats (SHR;B ) in the presence or absence of 2% isoflurane. Results are expressed as percent of values obtained in control cells. *P < 0.05, treated versus control cells.