Fig. 4. Time course of withdrawal latency in relation to noxious thermal stimulation in the contralateral limb with sham operation (A ) and in the hind paw with induction of chronic constriction nerve injury (B ). 4 μg Ab + EP = intrathecal 4 μg c-Fos antibody via  electroporation; 4 μg Ab only = intrathecal 4 μg c-Fos antibody without electroporation; NS Ab + EP = intrathecal 4 μg nonspecific antibody via  electroporation; 0.4 μg Ab + EP = intrathecal 0.4 μg c-Fos antibody via  electroporation; vehicle = saline only. For all groups, n = 6 and values are mean ± SEM. *Different from value for vehicle group (P < 0.05).