Fig. 3. Response to mechanical stimulation with von Frey hair in the saphenous skin territory for bupivacaine-loaded microspheres (BLM)–treated (n = 12) and spared nerve injury (SNI) control animals (n = 11). Both groups display a rapid decrease in threshold (P < 0.05 between baseline and each group at day 14) without a significant difference between the groups (P > 0.05) after day 14.